Fatal illness associated with a new hantavirus in Louisiana

Ali S. Khan, Christina F. Spiropoulou, Sergey Morzunov, Sherif R. Zaki, Melvin A. Kohn, Soheir R. Nawas, Louise McFarland, Stuart T. Nichol

Research output: Contribution to journalArticlepeer-review

67 Scopus citations


A fatal case of hantaviral illness occurred in Louisiana, outside of the range of P. maniculatus, the rodent reservoir for Sin Nombre virus. Hantavirus RNA and antigens were detected in patient autopsy tissues, and nucleotide sequence analysis of amplified polymerase chain reaction (PCR) products identified a newly recognized unique hantavirus, provisionally named Bayou virus. Prominent features of the clinical illness are compatible with hantavirus pulmonary syndrome (HPS), but several features such as renal insufficiency and intraalveolar hemorrhage are more compatible with hemorrhagic fever with renal syndrome (HFRS), a disease associated with Eurasian hantaviruses. © 1995 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)281-286
Number of pages6
JournalJournal of Medical Virology
Issue number3
StatePublished - Jul 1995
Externally publishedYes


  • Bayou virus
  • HFRS
  • Sin Nombre virus
  • bunyaviridae
  • hantavirus pulmonary syndrome
  • hantaviruses
  • nephropathy

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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