Fatal illness associated with a new hantavirus in Louisiana

Ali S. Khan; Christina F. Spiropoulou; Sergey Morzunov; Sherif R. Zaki; Melvin A. Kohn; Soheir R. Nawas; Louise McFarland; Stuart T. Nichol

doi:10.1002/jmv.1890460320

Fatal illness associated with a new hantavirus in Louisiana

Ali S. Khan, Christina F. Spiropoulou, Sergey Morzunov, Sherif R. Zaki, Melvin A. Kohn, Soheir R. Nawas, Louise McFarland, Stuart T. Nichol

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Abstract

A fatal case of hantaviral illness occurred in Louisiana, outside of the range of P. maniculatus, the rodent reservoir for Sin Nombre virus. Hantavirus RNA and antigens were detected in patient autopsy tissues, and nucleotide sequence analysis of amplified polymerase chain reaction (PCR) products identified a newly recognized unique hantavirus, provisionally named Bayou virus. Prominent features of the clinical illness are compatible with hantavirus pulmonary syndrome (HPS), but several features such as renal insufficiency and intraalveolar hemorrhage are more compatible with hemorrhagic fever with renal syndrome (HFRS), a disease associated with Eurasian hantaviruses. © 1995 Wiley‐Liss, Inc.

Original language	English (US)
Pages (from-to)	281-286
Number of pages	6
Journal	Journal of Medical Virology
Volume	46
Issue number	3
DOIs	https://doi.org/10.1002/jmv.1890460320
State	Published - Jul 1995
Externally published	Yes

Keywords

Bayou virus
HFRS
Sin Nombre virus
bunyaviridae
hantavirus pulmonary syndrome
hantaviruses
nephropathy

ASJC Scopus subject areas

Virology
Infectious Diseases

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10.1002/jmv.1890460320

Cite this

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title = "Fatal illness associated with a new hantavirus in Louisiana",

abstract = "A fatal case of hantaviral illness occurred in Louisiana, outside of the range of P. maniculatus, the rodent reservoir for Sin Nombre virus. Hantavirus RNA and antigens were detected in patient autopsy tissues, and nucleotide sequence analysis of amplified polymerase chain reaction (PCR) products identified a newly recognized unique hantavirus, provisionally named Bayou virus. Prominent features of the clinical illness are compatible with hantavirus pulmonary syndrome (HPS), but several features such as renal insufficiency and intraalveolar hemorrhage are more compatible with hemorrhagic fever with renal syndrome (HFRS), a disease associated with Eurasian hantaviruses. {\textcopyright} 1995 Wiley‐Liss, Inc.",

keywords = "Bayou virus, HFRS, Sin Nombre virus, bunyaviridae, hantavirus pulmonary syndrome, hantaviruses, nephropathy",

author = "Khan, {Ali S.} and Spiropoulou, {Christina F.} and Sergey Morzunov and Zaki, {Sherif R.} and Kohn, {Melvin A.} and Nawas, {Soheir R.} and Louise McFarland and Nichol, {Stuart T.}",

year = "1995",

month = jul,

doi = "10.1002/jmv.1890460320",

language = "English (US)",

volume = "46",

pages = "281--286",

journal = "Journal of Medical Virology",

issn = "0146-6615",

publisher = "Wiley-Liss Inc.",

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T1 - Fatal illness associated with a new hantavirus in Louisiana

AU - Khan, Ali S.

AU - Spiropoulou, Christina F.

AU - Morzunov, Sergey

AU - Zaki, Sherif R.

AU - Kohn, Melvin A.

AU - Nawas, Soheir R.

AU - McFarland, Louise

AU - Nichol, Stuart T.

PY - 1995/7

Y1 - 1995/7

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AB - A fatal case of hantaviral illness occurred in Louisiana, outside of the range of P. maniculatus, the rodent reservoir for Sin Nombre virus. Hantavirus RNA and antigens were detected in patient autopsy tissues, and nucleotide sequence analysis of amplified polymerase chain reaction (PCR) products identified a newly recognized unique hantavirus, provisionally named Bayou virus. Prominent features of the clinical illness are compatible with hantavirus pulmonary syndrome (HPS), but several features such as renal insufficiency and intraalveolar hemorrhage are more compatible with hemorrhagic fever with renal syndrome (HFRS), a disease associated with Eurasian hantaviruses. © 1995 Wiley‐Liss, Inc.

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KW - HFRS

KW - Sin Nombre virus

KW - bunyaviridae

KW - hantavirus pulmonary syndrome

KW - hantaviruses

KW - nephropathy

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Fatal illness associated with a new hantavirus in Louisiana

Abstract

Keywords

ASJC Scopus subject areas

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