Feeding patterns of rats chronically ingesting an ethanol-containing liquid diet

Roger D. Reidelberger, Dean J. Tuma, Todd A. Woltman, Terrence M. Donohue

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


We compared the feeding patterns of rata ingesting a 36% ethanol- containing liquid diet for 30 days with those of rats pair-fed an isocaloric liquid control diet or provided control diet or ground rat chow ad libitum. Ethanol-fed rats consumed fewer calories per day and gained less body weight than rate fed control diets ad libitum. Daily caloric intakes were ~50% lower during the first 10 days and 20% thereafter. Lower intakes in ethanol- fed rats occurred through a decrease in mean meal size rather than number of meals per day, although meals were moro evenly distributed diurnally. Pair- fed rata ingested most of their food in one or two meals within a few hours of presentation. In a related experiment, a 4-hr duodenal infusion of ethanol st a rate comparable to that of ethanol ingestion resulted in plasma ethanol levels of 28 ± 4 mM and suppressed 5-hr intake by ~40% by increasing the mean postmeal interval and satiety ratio. These results suggest that the suppressive effect of ethanol ingestion on food intake may be mediated in part by a post-gastric mechanism of ethanol action.

Original languageEnglish (US)
Pages (from-to)1275-1282
Number of pages8
JournalAlcoholism: Clinical and Experimental Research
Issue number7
StatePublished - 1996


  • Alcohol
  • Blood Alcohol
  • Food Intake
  • Small Intestine

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health


Dive into the research topics of 'Feeding patterns of rats chronically ingesting an ethanol-containing liquid diet'. Together they form a unique fingerprint.

Cite this