Fetal sex and maternal asthma control in pregnancy

Ludmila N. Bakhireva, Michael Schatz, Kenneth Lyons Jones, Carey M. Tucker, Donald J. Slymen, Hillary S. Klonoff-Cohen, Louise Gresham, Diana Johnson, Christina D. Chambers, D. Quinn, D. Vogt, K. Kao, S. Lavigne, J. Brochu, B. Buehler, E. Conover, K. Ormond, C. Chou, Y. Johnson, S. SwercS. Braddock, P. Slusher, L. Robinson, S. Gangell, G. Koren, M. Morreti, L. Wolfe, J. Carey, J. Robertson, J. Polifka, E. Rudy

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Asthma is a prevalent chronic disorder that might substantially complicate pregnancy. Some recent reports suggest that the presence of a female fetus might be associated with worse maternal asthma symptoms during pregnancy. We tested this hypothesis using the sample of 719 pregnant women with asthma prospectively enrolled in the OTIS study. The presence of a female fetus was associated with a higher incidence of hospitalizations for asthma during pregnancy (OR = 1.84; 95% CI: 1.05; 3.21) independent of maternal age, BMI, ethnicity, smoking, and socioeconomic status. The current study suggests that pregnant asthmatic women carrying a girl might be more susceptible to asthma exacerbations.

Original languageEnglish (US)
Pages (from-to)403-407
Number of pages5
JournalJournal of Asthma
Volume45
Issue number5
DOIs
StatePublished - Jun 1 2008

Keywords

  • Asthma
  • Asthma control
  • Asthma exacerbation
  • Fetal sex
  • Pregnancy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

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  • Cite this

    Bakhireva, L. N., Schatz, M., Jones, K. L., Tucker, C. M., Slymen, D. J., Klonoff-Cohen, H. S., Gresham, L., Johnson, D., Chambers, C. D., Quinn, D., Vogt, D., Kao, K., Lavigne, S., Brochu, J., Buehler, B., Conover, E., Ormond, K., Chou, C., Johnson, Y., ... Rudy, E. (2008). Fetal sex and maternal asthma control in pregnancy. Journal of Asthma, 45(5), 403-407. https://doi.org/10.1080/02770900801971826