Although fast atom bombardment (FAB) is often the method of choice for the analysis of nonvolatile, polar, and thermally labile samples, there are many instances where FAB is unable to produce meaningful spectra. FAB and field desorption (FD) have been recognized as complementary techniques in such cases and FD will typically provide molecular ion information. However, the lack of fragment ions for use in structure determination is a disadvantage. FD combined with MS/MS has been shown to provide this kind of information. Field ionization (FI) is known to produce intense molecular ion species and can be used in conjunction with MS/MS to obtain both molecular weight information and structurally important fragmentation patterns.
|Original language||English (US)|
|Title of host publication||Annual Conference on Mass Spectrometry and Allied Topics|
|Editors||Robert E. Finnigan|
|Publisher||American Soc for Mass Spectrometry|
|Number of pages||2|
|State||Published - 1984|
ASJC Scopus subject areas