First in-vivo studies of presbyopia treatment with ultrashort laserpulses

T. Ripken, A. Heisterkamp, U. Oberheide, R. R. Krueger, E. Luetkefels, W. Drommer, W. Ertmer, H. Lubatschowski

Research output: Contribution to journalConference articlepeer-review

9 Scopus citations


The most probable reason for presbyopia, the age-related loss of the accomodation-ability of the eye, is an age-related loss of the elasticity of the lens. To increase the elasticity, resp. regain elasticity we performed different fs-laser-induced cuts with an near-infrared 5 kHz femtosecond laser inside ex-vivo and in-vivo rabbit lenses. Sagittal and annulus cutting patterns in the lens were produced by focusing the laser beam through the cornea inside the lens and creating a laser induced optical breakdown. The cutting results were recorded with light microscopy and finally, after euthanization, changes in the optical fibers of the lens tissue were described.

Original languageEnglish (US)
Pages (from-to)137-145
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - 2003
Externally publishedYes
EventTherapeutic Laser Applications and Laser-Tissue Interactions - Munich, Germany
Duration: Jun 24 2003Jun 25 2003


  • Femtosecond laser
  • Ophthalmology
  • Presbyopia
  • Ultrafast laser

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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