Abstract
Neonatal enteroviral sepsis is a potentially fatal condition. Perinatally acquired infection and severe coagulopathy can be associated with a poor clinical outcome, and antiviral therapy is currently unavailable. Pocapavir (V-073) is an investigational drug candidate being developed for poliovirus indications, but also has variable antiviral activity against nonpolio enteroviruses. We describe the first use of pocapavir in treating a case of severe neonatal enteroviral sepsis due to Coxsackievirus B3.
Original language | English (US) |
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Pages (from-to) | 52-54 |
Number of pages | 3 |
Journal | Pediatric Infectious Disease Journal |
Volume | 34 |
Issue number | 1 |
DOIs | |
State | Published - 2015 |
Externally published | Yes |
Keywords
- Coxsackievirus
- Neonatal enterovirus infection
- Pocapavir
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Microbiology (medical)
- Infectious Diseases