Fluorescent chemosensors for carbohydrates: A decade's worth of bright spies for saccharides in review

Haishi Cao, Michael D. Heagy

Research output: Contribution to journalReview article

156 Scopus citations


This review provides a chronological survey of over fifty fluorescent chemosensors for carbohydrates from the period between 1992 to the present. The survey contains only those sensors that are synthetic or chemosensory, utilize boronic acids and display a fluorescence response in the form of intensity changes or shifts in wavelength. With each compound listed, a description of the saccharide probe is given with regard to concentration, excitation and emission wavelengths, pH and solvent mixture proportions. In addition, the selectivity of each chemosensor is provided as well as the trends in binding constants. Where possible, a description of the fluorescence signaling mechanism is given as well as commentary on the probe's unique features within this class of sensors.

Original languageEnglish (US)
Pages (from-to)569-584
Number of pages16
JournalJournal of Fluorescence
Issue number5
StatePublished - Sep 1 2004



  • Boronic acids
  • FRET
  • Fluorescent probes
  • ICT
  • PET
  • Saccharides

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Psychology
  • Social Sciences (miscellaneous)
  • Sociology and Political Science
  • Spectroscopy
  • Clinical Biochemistry
  • Law

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