Fluxional additives: A second generation control in enantioselective catalysis

Mukund P. Sibi, Shankar Manyem, Hector Palencia

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


The concept of "fluxional additives", additives that can adopt enantiomeric conformations depending on the chiral information in the ligand, is demonstrated in enantioselective Diels-Alder and nitrone cycloaddition reactions. The additive design is modular, and diverse structures are accessible in three steps. Chiral Lewis acids from main group and transition metals show enhancements in enantioselectivity in the presence of these additives.

Original languageEnglish (US)
Pages (from-to)13660-13661
Number of pages2
JournalJournal of the American Chemical Society
Issue number42
StatePublished - Oct 25 2006

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Fingerprint Dive into the research topics of 'Fluxional additives: A second generation control in enantioselective catalysis'. Together they form a unique fingerprint.

Cite this