Fournier's gangrene complicating aggressive therapy for hematologic malignancy

Alan Berg, James O. Armitage, C. Patrick Burns

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

The authors describe two cases of Fournier's gangrene complicating aggressive therapy for hematologic malignancies. Fournier's gangrene is a fulminant necrotizing fasciitis of the scrotum and penis, often with an infectious etiology. Only one prior case has been reported in a patient receiving aggressive chemotherapy for a hematologic malignancy. Unique to these three cases was profound granulocytopenia and the culturing of Pseudomonas aeruginosa in both the blood and necrotic perineal—scrotal tissue. Maintaining a high index of suspicion with early recognition and aggressive therapy may decrease the morbidity and mortality of this devastating and life‐threatening infection in the compromised host. Cancer 57:2291–2294, 1986.

Original languageEnglish (US)
Pages (from-to)2291-2294
Number of pages4
JournalCancer
Volume57
Issue number12
DOIs
StatePublished - Jun 15 1986

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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