Fragment-based and structure-guided discovery and optimization of Rho kinase inhibitors

Rongshi Li, Mathew P. Martin, Yan Liu, Binglin Wang, Ronil A. Patel, Jin Yi Zhu, Nan Sun, Roberta Pireddu, Nicholas J. Lawrence, Jiannong Li, Eric B. Haura, Shen Shu Sung, Wayne C. Guida, Ernst Schonbrunn, Said M. Sebti

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