Full genomic characterization of a saffold virus isolated in Peru

Mariana Leguia, Steev Loyola, Jane Rios, Diana Juarez, Carolina Guevara, Maria Silva, Karla Prieto, Michael Wiley, Matthew R. Kasper, Gustavo Palacios, Daniel G. Bausch

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas.

Original languageEnglish (US)
Pages (from-to)816-825
Number of pages10
JournalPathogens
Volume4
Issue number4
DOIs
StatePublished - Nov 20 2015
Externally publishedYes

Keywords

  • Cardiovirus
  • Full genome
  • Peru
  • Saffold virus

ASJC Scopus subject areas

  • Immunology and Allergy
  • Molecular Biology
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

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