Full genomic characterization of a saffold virus isolated in Peru

Mariana Leguia; Steev Loyola; Jane Rios; Diana Juarez; Carolina Guevara; Maria Silva; Karla Prieto; Michael Wiley; Matthew R. Kasper; Gustavo Palacios; Daniel G. Bausch

doi:10.3390/pathogens4040816

Full genomic characterization of a saffold virus isolated in Peru

Mariana Leguia, Steev Loyola, Jane Rios, Diana Juarez, Carolina Guevara, Maria Silva, Karla Prieto, Michael Wiley, Matthew R. Kasper, Gustavo Palacios, Daniel G. Bausch

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas.

Original language	English (US)
Pages (from-to)	816-825
Number of pages	10
Journal	Pathogens
Volume	4
Issue number	4
DOIs	https://doi.org/10.3390/pathogens4040816
State	Published - Nov 20 2015
Externally published	Yes

Keywords

Cardiovirus
Full genome
Peru
Saffold virus

ASJC Scopus subject areas

Immunology and Allergy
Molecular Biology
General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases

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10.3390/pathogens4040816

Cite this

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title = "Full genomic characterization of a saffold virus isolated in Peru",

abstract = "While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas.",

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T1 - Full genomic characterization of a saffold virus isolated in Peru

AU - Leguia, Mariana

AU - Loyola, Steev

AU - Rios, Jane

AU - Juarez, Diana

AU - Guevara, Carolina

AU - Silva, Maria

AU - Prieto, Karla

AU - Wiley, Michael

AU - Kasper, Matthew R.

AU - Palacios, Gustavo

AU - Bausch, Daniel G.

PY - 2015/11/20

Y1 - 2015/11/20

N2 - While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas.

AB - While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas.

KW - Cardiovirus

KW - Full genome

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KW - Saffold virus

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Full genomic characterization of a saffold virus isolated in Peru

Abstract

Keywords

ASJC Scopus subject areas

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