TY - JOUR
T1 - Fungal morphogenesis
AU - Lin, Xiaorong
AU - Andrew Alspaugh, J.
AU - Liu, Haoping
AU - Harris, Steven
N1 - Publisher Copyright:
© 2015 Cold Spring Harbor Laboratory Press; all rights reserved.
PY - 2015
Y1 - 2015
N2 - Morphogenesis in fungi is often induced by extracellular factors and executed by fungal genetic factors. Cell surface changes and alterations of the microenvironment often accompany morphogenetic changes in fungi. In this review, we will first discuss the general traits of yeast and hyphal morphotypes and how morphogenesis affects development and adaptation by fungi to their native niches, including host niches. Then we will focus on the molecular machinery responsible for the two most fundamental growth forms, yeast and hyphae. Last, we will describe how fungi incorporate exogenous environmental and host signals together with genetic factors to determine their morphotype and how morphogenesis, in turn, shapes the fungal microenvironment.
AB - Morphogenesis in fungi is often induced by extracellular factors and executed by fungal genetic factors. Cell surface changes and alterations of the microenvironment often accompany morphogenetic changes in fungi. In this review, we will first discuss the general traits of yeast and hyphal morphotypes and how morphogenesis affects development and adaptation by fungi to their native niches, including host niches. Then we will focus on the molecular machinery responsible for the two most fundamental growth forms, yeast and hyphae. Last, we will describe how fungi incorporate exogenous environmental and host signals together with genetic factors to determine their morphotype and how morphogenesis, in turn, shapes the fungal microenvironment.
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U2 - 10.1101/cshperspect.a019679
DO - 10.1101/cshperspect.a019679
M3 - Article
C2 - 25367976
AN - SCOPUS:84923766007
VL - 5
JO - Cold Spring Harbor perspectives in medicine
JF - Cold Spring Harbor perspectives in medicine
SN - 2157-1422
IS - 2
M1 - a019679
ER -