TY - JOUR
T1 - Fungi inhabiting the healthy human gastrointestinal tract
T2 - A diverse and dynamic community
AU - Hallen-Adams, Heather E.
AU - Kachman, Stephen D.
AU - Kim, Jaehyoung
AU - Legge, Ryan M.
AU - Martínez, Inés
N1 - Publisher Copyright:
© 2015 Elsevier Ltd and The British Mycological Society.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Fungal DNA was selectively amplified, and the ITS region sequenced, from fecal samples taken from 45 healthy human volunteers at one (21 volunteers) or two (24 volunteers) time points. Seventy-two operational taxonomic units, representing two phyla and ten classes of fungi, were recovered. Candida yeasts, notably Candida tropicalis (present in 51 samples), and yeasts in the Dipodascaceae (39 samples), dominated, while 38 OTUs were detected in a single sample each. Fungi included known human symbionts (. Candida, Cryptococcus, Malassezia and Trichosporon spp.), common airborne fungi (. Cladosporium sp.) and fungi known to be associated with food (. Debaryomyces hansenii and high salt fermented foods; Penicillium roqueforti and blue cheese). In contrast with gut-associated bacteria, fungi occurred in much lower abundance and diversity, and fungal composition appeared unstable over time.
AB - Fungal DNA was selectively amplified, and the ITS region sequenced, from fecal samples taken from 45 healthy human volunteers at one (21 volunteers) or two (24 volunteers) time points. Seventy-two operational taxonomic units, representing two phyla and ten classes of fungi, were recovered. Candida yeasts, notably Candida tropicalis (present in 51 samples), and yeasts in the Dipodascaceae (39 samples), dominated, while 38 OTUs were detected in a single sample each. Fungi included known human symbionts (. Candida, Cryptococcus, Malassezia and Trichosporon spp.), common airborne fungi (. Cladosporium sp.) and fungi known to be associated with food (. Debaryomyces hansenii and high salt fermented foods; Penicillium roqueforti and blue cheese). In contrast with gut-associated bacteria, fungi occurred in much lower abundance and diversity, and fungal composition appeared unstable over time.
KW - CTG yeasts
KW - Candida
KW - Human gut microbiome
KW - Malassezia
UR - http://www.scopus.com/inward/record.url?scp=84929616574&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929616574&partnerID=8YFLogxK
U2 - 10.1016/j.funeco.2015.01.006
DO - 10.1016/j.funeco.2015.01.006
M3 - Article
AN - SCOPUS:84929616574
SN - 1754-5048
VL - 15
SP - 9
EP - 17
JO - Fungal Ecology
JF - Fungal Ecology
ER -