Gamma oscillations in the primary motor cortex studied with MEG

Xiaolin Huo, Jing Xiang, Yingying Wang, Elijah G. Kirtman, Rupesh Kotecha, Hisako Fujiwara, Nat Hemasilpin, Douglas F. Rose, Ton Degrauw

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

In recent years, there has been a growing interest on the role of gamma band (>30. Hz) neural oscillations in motor control, although the function of this activity in motor control is unknown clearly. With the goal of discussing the high frequency sources non-invasively and precisely during unilateral index finger movement, we investigated gamma band oscillations in 20 right-handed normal adults with magnetoencephalography (MEG). The results showed that gamma band activity appeared only during finger movement. Nineteen subjects displayed consistently contralateral event-related synchronization (C-ERS) within high gamma band (70-150. Hz) in primary motor cortex (M1) of both hemispheres. Interestingly, 15 subjects displayed ipsilateral event-related desynchronization (I-ERD) and C-ERS within broad gamma band (30-150. Hz). The locations of the broad gamma band I-ERD and C-ERS revealed hemispherical symmetry in M1. These findings demonstrate that there are consistent high gamma C-ERS and inconsistent low gamma I-ERD during a simple finger movement in the motor cortex. This study provides new evidence for the use of high gamma frequency oscillations as biomarkers in the analyses of functional brain activity and the localization of the motor cortex.

Original languageEnglish (US)
Pages (from-to)619-624
Number of pages6
JournalBrain and Development
Volume32
Issue number8
DOIs
StatePublished - Sep 2010

Keywords

  • Event-related desynchronization (ERD)
  • Event-related synchronization (ERS)
  • Magnetoencephalography (MEG)
  • Sensorimotor cortex
  • Synthetic aperture magnetometry (SAM)
  • Time-frequency analysis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology

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