General health and life satisfaction in children with chronic illness

Courtney K. Blackwell, Amy J. Elliott, Jody Ganiban, Julie Herbstman, Kelly Hunt, Christopher B. Forrest, Carlos A. Camargo

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


OBJECTIVES: To investigate children’s general health and life satisfaction in the context of chronic illness. METHODS: Caregivers (n = 1113) from 3 concurrent cohort studies completed the Patient-Reported Outcomes Measurement Information System Parent-Proxy Global Health measure, which is used to assess a child’s overall physical, mental, and social health, as well as the Patient-Reported Outcomes Measurement Information System Parent-Proxy Life Satisfaction measure between March 2017 and December 2017 for 1253 children aged 5 to 9 years. We harmonized demographic factors and family environmental stressors (single parent, maternal mental health, and income) to common metrics across the cohorts. To examine associations between chronic illness and children’s general health and life satisfaction, we fit linear regression models with cohort fixed effects and accounted for the multilevel data structure of multiple children nested within the same family (ie, twins and other siblings) with generalized estimating equations. RESULTS: Children with chronic illness had worse general health than those without illness (adjusted b = 21.20; 95% confidence interval: 22.49 to 0.09). By contrast, children with chronic illness had similar levels of life satisfaction (adjusted b = 2.19; 95% confidence interval: 21.25 to 0.87). Additionally, children’s psychological stress had the strongest negative association with both outcomes, even after adjusting for demographics and family environmental stressors. CONCLUSIONS: Although children with chronic illness have lower parent-reported general health, their life satisfaction appears comparable with that of peers without chronic illness. With this study, we provide evidence that chronic illnesses do not preclude children from leading happy and satisfying lives.

Original languageEnglish (US)
Article numbere20182988
Issue number6
StatePublished - 2019

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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