TY - JOUR
T1 - Genetic analysis of dyslexia and other complex behavioral phenotypes
AU - Pennington, Bruce F.
AU - Smith, Shelley D.
PY - 1997
Y1 - 1997
N2 - In this review, we discuss recent data on the genetics of developmental dyslexia and consider broader issues involved in the search for genes influencing complex behavioral phenotypes. These issues include 1) the need for a sophisticated analysis of the phenotype and the need for interdisciplinary collaboration between geneticists and cognitive neuroscientists, 2) the likelihood of genetic heterogeneity and non-Mendelian inheritance and the necessity for linkage methods to deal with these issues, and 3) how association analyses complement linkage analyses.
AB - In this review, we discuss recent data on the genetics of developmental dyslexia and consider broader issues involved in the search for genes influencing complex behavioral phenotypes. These issues include 1) the need for a sophisticated analysis of the phenotype and the need for interdisciplinary collaboration between geneticists and cognitive neuroscientists, 2) the likelihood of genetic heterogeneity and non-Mendelian inheritance and the necessity for linkage methods to deal with these issues, and 3) how association analyses complement linkage analyses.
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U2 - 10.1097/00008480-199712000-00014
DO - 10.1097/00008480-199712000-00014
M3 - Review article
C2 - 9425598
AN - SCOPUS:0031436594
SN - 1040-8703
VL - 9
SP - 636
EP - 641
JO - Current Opinion in Pediatrics
JF - Current Opinion in Pediatrics
IS - 6
ER -