Genetic basis of hybrid male sterility among three closely related species of Drosophila

Paras Kumar Mishra, B. N. Singh

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The genetic basis of hybrid male sterility among three closely related species, Drosophila bipectinata, D. parabipectinata and D. malerkotliana has been investigated by using backcross analysis methods. The role of Y chromosome, major hybrid sterility (MHS) genes (genetic factors) and cytoplasm (non-genetic factor) have been studied in the hybrids of these three species. In the species pair, bipectinata - parabipectinata, Y chromosome introgression of parabipectinata in the genomic background of bipectinata and the reciprocal Y chromosome introgression were unsuccessful as all males in second backcross generation were sterile. Neither MHS genes nor cytoplasm was found important for sterility. This suggests the involvement of X-Y, X-autosomes or polygenic interactions in hybrid male sterility. In bipectinata - malerkotliana and parabipectinata - malerkotliana species pairs, Y chromosome substitution in reciprocal crosses did not affect male fertility. Backcross analyses also show no involvement of MHS genes or cytoplasm in hybrid male sterility in these two species pairs. Therefore, X- autosome interaction or polygenic interaction is supposed to be involved in hybrid male sterility in these two species pairs. These findings also provide evidence that even in closely related species, genetic interactions underlying hybrid male sterility may vary.

Original languageEnglish (US)
Pages (from-to)455-461
Number of pages7
JournalIndian journal of experimental biology
Volume43
Issue number5
StatePublished - May 2005

Keywords

  • Drosophila
  • Genetic analysis
  • Hybrid male sterility

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Biology
  • Cell Biology

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