Genetic comparison of ovine and bovine pestiviruses.

C. L. Kelling, J. E. Kennedy, L. C. Stine, K. K. Rump, P. S. Paul, J. E. Partridge

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Viral RNA oligonucleotide fingerprinting was used to compare genetic relationship among pestiviruses originating from ovine or bovine host species. Ovine pestiviruses, including reference border disease virus and 2 border disease isolates originating from natural pestivirus infections of sheep, appeared to have a more distant genetic relationship among themselves than with certain bovine pestiviruses. A closer genetic relatedness was evident between border disease virus and 3 noncytopathic bovine pestiviruses, including Draper bovine viral diarrhea virus (BVDV), a BVDV isolate that originated from aborted bovine fetuses, and a virus that was isolated from the serum of a calf that had a chronic BVDV infection. Four noncytopathic bovine viruses, including Draper BVDV and 3 field isolates, were closely related. Reference Oregon C24V BVDV, a cytopathic virus, was closely related to only 1 of the 7 noncytopathic viruses in this study.

Original languageEnglish (US)
Pages (from-to)2019-2024
Number of pages6
JournalAmerican journal of veterinary research
Issue number12
StatePublished - Dec 1990

ASJC Scopus subject areas

  • General Veterinary


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