Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

Samir Gupta; Dawn Provenzale; Xavier Llor; Amy L. Halverson; William Grady; Daniel C. Chung; Sigurdis Haraldsdottir; Arnold J. Markowitz; Thomas P. Slavin; Heather Hampel; Reid M. Ness; Jennifer M. Weiss; Dennis J. Ahnen; Lee May Chen; Gregory Cooper; Dayna S. Early; Francis M. Giardiello; Michael J. Hall; Stanley R. Hamilton; Priyanka Kanth; Jason B. Klapman; Audrey J. Lazenby; Patrick M. Lynch; Robert J. Mayer; June Mikkelson; Shajan Peter; Scott E. Regenbogen; Mary A. Dwyer; Ndiya Ogba

doi:10.6004/jnccn.2019.0044

Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

Samir Gupta, Dawn Provenzale, Xavier Llor, Amy L. Halverson, William Grady, Daniel C. Chung, Sigurdis Haraldsdottir, Arnold J. Markowitz, Thomas P. Slavin, Heather Hampel, Reid M. Ness, Jennifer M. Weiss, Dennis J. Ahnen, Lee May Chen, Gregory Cooper, Dayna S. Early, Francis M. Giardiello, Michael J. Hall, Stanley R. Hamilton, Priyanka KanthJason B. Klapman, Audrey J. Lazenby, Patrick M. Lynch, Robert J. Mayer, June Mikkelson, Shajan Peter, Scott E. Regenbogen, Mary A. Dwyer, Ndiya Ogba

Research output: Contribution to journal › Article › peer-review

189 Scopus citations

Abstract

Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

Original language	English (US)
Pages (from-to)	1032-1041
Number of pages	10
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	17
Issue number	9
DOIs	https://doi.org/10.6004/jnccn.2019.0044
State	Published - 2019

ASJC Scopus subject areas

Oncology

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Gupta, S., Provenzale, D., Llor, X., Halverson, A. L., Grady, W., Chung, D. C., Haraldsdottir, S., Markowitz, A. J., Slavin, T. P., Hampel, H., Ness, R. M., Weiss, J. M., Ahnen, D. J., Chen, L. M., Cooper, G., Early, D. S., Giardiello, F. M., Hall, M. J., Hamilton, S. R., ... Ogba, N. (2019). Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines. JNCCN Journal of the National Comprehensive Cancer Network, 17(9), 1032-1041. https://doi.org/10.6004/jnccn.2019.0044

Gupta, S, Provenzale, D, Llor, X, Halverson, AL, Grady, W, Chung, DC, Haraldsdottir, S, Markowitz, AJ, Slavin, TP, Hampel, H, Ness, RM, Weiss, JM, Ahnen, DJ, Chen, LM, Cooper, G, Early, DS, Giardiello, FM, Hall, MJ, Hamilton, SR, Kanth, P, Klapman, JB, Lazenby, AJ, Lynch, PM, Mayer, RJ, Mikkelson, J, Peter, S, Regenbogen, SE, Dwyer, MA & Ogba, N 2019, 'Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines', JNCCN Journal of the National Comprehensive Cancer Network, vol. 17, no. 9, pp. 1032-1041. https://doi.org/10.6004/jnccn.2019.0044

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title = "Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines",

abstract = "Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.",

author = "Samir Gupta and Dawn Provenzale and Xavier Llor and Halverson, {Amy L.} and William Grady and Chung, {Daniel C.} and Sigurdis Haraldsdottir and Markowitz, {Arnold J.} and Slavin, {Thomas P.} and Heather Hampel and Ness, {Reid M.} and Weiss, {Jennifer M.} and Ahnen, {Dennis J.} and Chen, {Lee May} and Gregory Cooper and Early, {Dayna S.} and Giardiello, {Francis M.} and Hall, {Michael J.} and Hamilton, {Stanley R.} and Priyanka Kanth and Klapman, {Jason B.} and Lazenby, {Audrey J.} and Lynch, {Patrick M.} and Mayer, {Robert J.} and June Mikkelson and Shajan Peter and Regenbogen, {Scott E.} and Dwyer, {Mary A.} and Ndiya Ogba",

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doi = "10.6004/jnccn.2019.0044",

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AU - Gupta, Samir

AU - Provenzale, Dawn

AU - Llor, Xavier

AU - Halverson, Amy L.

AU - Grady, William

AU - Chung, Daniel C.

AU - Haraldsdottir, Sigurdis

AU - Markowitz, Arnold J.

AU - Slavin, Thomas P.

AU - Hampel, Heather

AU - Ness, Reid M.

AU - Weiss, Jennifer M.

AU - Ahnen, Dennis J.

AU - Chen, Lee May

AU - Cooper, Gregory

AU - Early, Dayna S.

AU - Giardiello, Francis M.

AU - Hall, Michael J.

AU - Hamilton, Stanley R.

AU - Kanth, Priyanka

AU - Klapman, Jason B.

AU - Lazenby, Audrey J.

AU - Lynch, Patrick M.

AU - Mayer, Robert J.

AU - Mikkelson, June

AU - Peter, Shajan

AU - Regenbogen, Scott E.

AU - Dwyer, Mary A.

AU - Ogba, Ndiya

PY - 2019

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AB - Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

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Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

Abstract

ASJC Scopus subject areas

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