Genotoxic effects of ketamine on CHO cells

S. G. Adhvaryu; A. H. Trivedi; K. H. Jani; R. C. Vyas; B. J. Dave

doi:10.1007/BF00286736

Genotoxic effects of ketamine on CHO cells

S. G. Adhvaryu, A. H. Trivedi, K. H. Jani, R. C. Vyas, B. J. Dave

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Ketamine, a non-barbiturate anaesthetic agent, was studied for its genotoxic potential using the SCE assay. It was genotoxic in the in vitro system at concentrations comparable to the plasma levels achieved during steady state anaesthesia. It had no effects on cellular kinetics in CHO cells.

Original language	English (US)
Pages (from-to)	124-125
Number of pages	2
Journal	Archives of Toxicology
Volume	59
Issue number	2
DOIs	https://doi.org/10.1007/BF00286736
State	Published - Jul 1986
Externally published	Yes

Keywords

CHO cells
Ketamine
Mutagenicity testings
Sister chromatid exchange assay

ASJC Scopus subject areas

Toxicology
Health, Toxicology and Mutagenesis

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10.1007/BF00286736

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title = "Genotoxic effects of ketamine on CHO cells",

abstract = "Ketamine, a non-barbiturate anaesthetic agent, was studied for its genotoxic potential using the SCE assay. It was genotoxic in the in vitro system at concentrations comparable to the plasma levels achieved during steady state anaesthesia. It had no effects on cellular kinetics in CHO cells.",

keywords = "CHO cells, Ketamine, Mutagenicity testings, Sister chromatid exchange assay",

author = "Adhvaryu, {S. G.} and Trivedi, {A. H.} and Jani, {K. H.} and Vyas, {R. C.} and Dave, {B. J.}",

year = "1986",

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AU - Adhvaryu, S. G.

AU - Trivedi, A. H.

AU - Jani, K. H.

AU - Vyas, R. C.

AU - Dave, B. J.

PY - 1986/7

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KW - Ketamine

KW - Mutagenicity testings

KW - Sister chromatid exchange assay

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Genotoxic effects of ketamine on CHO cells

Abstract

Keywords

ASJC Scopus subject areas

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