Giant cell reparative granuloma of the petrous temporal bone: A case report and literature review

Joy C. Williams, William E. Thoreil, John S. Trêves, Mary E. Fidler, Gary F. Moore, Lyal G. Leibrock

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Giant cell reparative granuloma (GCRG) is an unusual, benign bone lesion that most commonly affects the maxilla and mandible; skull involvement is rare. The etiology is uncertain but may be related to trauma. GCRG is difficult to distinguish from giant cell tumor of the bone and has a lower recurrence rate. Thirteen reports of temporal bone GCRG in 11 patients have been reported. One report of a petrous GCRG in a 3-year-old girl has been identified. A 38-year-old male presented with a 2-year history of fullness in his left ear, ipsilateral hearing loss, and intermittent cacosmia. Computed tomography and magnetic resonance imaging revealed a large left-sided anterior temporal extradural mass. The patient underwent a left frontotemporal craniotomy and resection of a left temporal fossa tumor that involved the petrous and squamous parts of the temporal bone. The patient's post-operative course was uneventful, except for increased hearing loss secondary to opening of the epitympanum. Follow-up at one month revealed no other problems. Histopathology of the specimen was consistent with a giant cell reparative granuloma.

Original languageEnglish (US)
Pages (from-to)89-93
Number of pages5
JournalSkull Base Surgery
Issue number2
StatePublished - 2000

ASJC Scopus subject areas

  • Clinical Neurology


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