TY - JOUR
T1 - Graphene-based materials for tissue engineering
AU - Shin, Su Ryon
AU - Li, Yi Chen
AU - Jang, Hae Lin
AU - Khoshakhlagh, Parastoo
AU - Akbari, Mohsen
AU - Nasajpour, Amir
AU - Zhang, Yu Shrike
AU - Tamayol, Ali
AU - Khademhosseini, Ali
N1 - Funding Information:
This paper was supported by National Science Foundation ( EFRI-1240443 ), ONR PECASE Award, and the National Institutes of Health ( HL092836 , DE019024 , EB012597 , AR057837 , DE021468 , HL099073 , EB008392 ).
Publisher Copyright:
© 2016
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Graphene and its chemical derivatives have been a pivotal new class of nanomaterials and a model system for quantum behavior. The material's excellent electrical conductivity, biocompatibility, surface area and thermal properties are of much interest to the scientific community. Two-dimensional graphene materials have been widely used in various biomedical research areas such as bioelectronics, imaging, drug delivery, and tissue engineering. In this review, we will highlight the recent applications of graphene-based materials in tissue engineering and regenerative medicine. In particular, we will discuss the application of graphene-based materials in cardiac, neural, bone, cartilage, skeletal muscle, and skin/adipose tissue engineering. We will also discuss the potential risk factors of graphene-based materials in tissue engineering. In conclusion, we will outline the opportunities in the usage of graphene-based materials for clinical applications.
AB - Graphene and its chemical derivatives have been a pivotal new class of nanomaterials and a model system for quantum behavior. The material's excellent electrical conductivity, biocompatibility, surface area and thermal properties are of much interest to the scientific community. Two-dimensional graphene materials have been widely used in various biomedical research areas such as bioelectronics, imaging, drug delivery, and tissue engineering. In this review, we will highlight the recent applications of graphene-based materials in tissue engineering and regenerative medicine. In particular, we will discuss the application of graphene-based materials in cardiac, neural, bone, cartilage, skeletal muscle, and skin/adipose tissue engineering. We will also discuss the potential risk factors of graphene-based materials in tissue engineering. In conclusion, we will outline the opportunities in the usage of graphene-based materials for clinical applications.
KW - Graphene
KW - Graphene oxide
KW - Graphene-based materials
KW - Regenerative medicine
KW - Tissue engineering
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U2 - 10.1016/j.addr.2016.03.007
DO - 10.1016/j.addr.2016.03.007
M3 - Review article
C2 - 27037064
AN - SCOPUS:84990878216
SN - 0169-409X
VL - 105
SP - 255
EP - 274
JO - Advanced Drug Delivery Reviews
JF - Advanced Drug Delivery Reviews
ER -