Graphene-based materials for tissue engineering

Su Ryon Shin, Yi Chen Li, Hae Lin Jang, Parastoo Khoshakhlagh, Mohsen Akbari, Amir Nasajpour, Yu Shrike Zhang, Ali Tamayol, Ali Khademhosseini

Research output: Contribution to journalReview article

209 Scopus citations

Abstract

Graphene and its chemical derivatives have been a pivotal new class of nanomaterials and a model system for quantum behavior. The material's excellent electrical conductivity, biocompatibility, surface area and thermal properties are of much interest to the scientific community. Two-dimensional graphene materials have been widely used in various biomedical research areas such as bioelectronics, imaging, drug delivery, and tissue engineering. In this review, we will highlight the recent applications of graphene-based materials in tissue engineering and regenerative medicine. In particular, we will discuss the application of graphene-based materials in cardiac, neural, bone, cartilage, skeletal muscle, and skin/adipose tissue engineering. We will also discuss the potential risk factors of graphene-based materials in tissue engineering. In conclusion, we will outline the opportunities in the usage of graphene-based materials for clinical applications.

Original languageEnglish (US)
Pages (from-to)255-274
Number of pages20
JournalAdvanced Drug Delivery Reviews
Volume105
DOIs
StatePublished - Oct 1 2016

Keywords

  • Graphene
  • Graphene oxide
  • Graphene-based materials
  • Regenerative medicine
  • Tissue engineering

ASJC Scopus subject areas

  • Pharmaceutical Science

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  • Cite this

    Shin, S. R., Li, Y. C., Jang, H. L., Khoshakhlagh, P., Akbari, M., Nasajpour, A., Zhang, Y. S., Tamayol, A., & Khademhosseini, A. (2016). Graphene-based materials for tissue engineering. Advanced Drug Delivery Reviews, 105, 255-274. https://doi.org/10.1016/j.addr.2016.03.007