Head and neck cancer in a developing country: A population-based perspective across 8 years

Esra Attar; Subhojit Dey; Ahmad Hablas; Ibrahim A. Seifeldin; Mohamed Ramadan; Laura S. Rozek; Amr S. Soliman

doi:10.1016/j.oraloncology.2010.05.002

Head and neck cancer in a developing country: A population-based perspective across 8 years

Esra Attar, Subhojit Dey, Ahmad Hablas, Ibrahim A. Seifeldin, Mohamed Ramadan, Laura S. Rozek, Amr S. Soliman

Epidemiology

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

Head and neck cancer (HNC) has been studied in different regions of the world but little is known about its incidence patterns in the Middle East and Egypt. In this study from Egypt's only population-based registry, we analyzed data from 1999 to 2006, to estimate incidence, incidence rate ratios (IRRs) and 95% confidence intervals (CIs) categorized by age, district and subsites. Overall urban incidence of HNC was twice or more that of rural incidence for both males (IRR = 2.59; 95% CI = 2.26, 2.97) and females (IRR = 2.00; 95% CI = 1.64, 2.43). Highest urban-rural difference for males was seen in 40-49 years (IRR = 2.79; 95% CI = 1.92, 4.05) and for females in 30-39 years (IRR = 2.94; 95% CI = 1.60, 5.40). Among subsites, highest incidence among males was for larynx (1.53/10⁵) and among females for gum and mouth (0.48/10 ⁵). Maximum urban-rural difference in males was for paranasal sinus (IRR = 4.66; 95% CI = 1.88, 11.54) and in females for lip (IRR = 8.91; 95% CI = 1.89, 41.98). The study underscores the patterns of HNC incidence in Egypt while indicating the need for future analytical studies investigating specific risk factors of HNC in this population.

Original language	English (US)
Pages (from-to)	591-596
Number of pages	6
Journal	Oral Oncology
Volume	46
Issue number	8
DOIs	https://doi.org/10.1016/j.oraloncology.2010.05.002
State	Published - Aug 2010

Keywords

Africa
Descriptive epidemiology
Egypt
Head and neck cancer
Risk factors
SEER
Urban-rural

ASJC Scopus subject areas

Oral Surgery
Oncology
Cancer Research

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10.1016/j.oraloncology.2010.05.002

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@article{4ac1d9922c714c17802acb8214206888,

title = "Head and neck cancer in a developing country: A population-based perspective across 8 years",

abstract = "Head and neck cancer (HNC) has been studied in different regions of the world but little is known about its incidence patterns in the Middle East and Egypt. In this study from Egypt's only population-based registry, we analyzed data from 1999 to 2006, to estimate incidence, incidence rate ratios (IRRs) and 95% confidence intervals (CIs) categorized by age, district and subsites. Overall urban incidence of HNC was twice or more that of rural incidence for both males (IRR = 2.59; 95% CI = 2.26, 2.97) and females (IRR = 2.00; 95% CI = 1.64, 2.43). Highest urban-rural difference for males was seen in 40-49 years (IRR = 2.79; 95% CI = 1.92, 4.05) and for females in 30-39 years (IRR = 2.94; 95% CI = 1.60, 5.40). Among subsites, highest incidence among males was for larynx (1.53/105) and among females for gum and mouth (0.48/10 5). Maximum urban-rural difference in males was for paranasal sinus (IRR = 4.66; 95% CI = 1.88, 11.54) and in females for lip (IRR = 8.91; 95% CI = 1.89, 41.98). The study underscores the patterns of HNC incidence in Egypt while indicating the need for future analytical studies investigating specific risk factors of HNC in this population.",

keywords = "Africa, Descriptive epidemiology, Egypt, Head and neck cancer, Risk factors, SEER, Urban-rural",

author = "Esra Attar and Subhojit Dey and Ahmad Hablas and Seifeldin, {Ibrahim A.} and Mohamed Ramadan and Rozek, {Laura S.} and Soliman, {Amr S.}",

note = "Funding Information: This work was supported in part by the Cancer Epidemiology Education in Special Populations (CEESP) Program of the University of Michigan (R25 CA112383 ). Funding Information: The Gharbiah population-based cancer registry, founded in 1998 as a part of the Middle East Cancer Consortium (MECC) and funded by the US National Cancer Institute (NCI), is located in Tanta, the capital of Gharbiah province. 9,18 Through an active registration process, data on cancer cases are collected from various sources in the province. For this study, yearly HNC cases came from three locations; the Tanta Cancer Center (40–50%), Gharbiah Cancer Society (10–12%) and Tanta University Hospital (10–12%). Data obtained from these hospitals and centers were entered in a manner that ensured strict quality control checks and avoided repetition of cases using the International Agency for Research on Cancer (IARC) software CanReg4. Registrars were trained in data extraction and entry methods, and are periodically monitored by faculty of Emory School of Public Health, IARC, and the MECC. 18 ",

year = "2010",

month = aug,

doi = "10.1016/j.oraloncology.2010.05.002",

language = "English (US)",

volume = "46",

pages = "591--596",

journal = "Oral Oncology",

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T1 - Head and neck cancer in a developing country

T2 - A population-based perspective across 8 years

AU - Attar, Esra

AU - Dey, Subhojit

AU - Hablas, Ahmad

AU - Seifeldin, Ibrahim A.

AU - Ramadan, Mohamed

AU - Rozek, Laura S.

AU - Soliman, Amr S.

N1 - Funding Information: This work was supported in part by the Cancer Epidemiology Education in Special Populations (CEESP) Program of the University of Michigan (R25 CA112383 ). Funding Information: The Gharbiah population-based cancer registry, founded in 1998 as a part of the Middle East Cancer Consortium (MECC) and funded by the US National Cancer Institute (NCI), is located in Tanta, the capital of Gharbiah province. 9,18 Through an active registration process, data on cancer cases are collected from various sources in the province. For this study, yearly HNC cases came from three locations; the Tanta Cancer Center (40–50%), Gharbiah Cancer Society (10–12%) and Tanta University Hospital (10–12%). Data obtained from these hospitals and centers were entered in a manner that ensured strict quality control checks and avoided repetition of cases using the International Agency for Research on Cancer (IARC) software CanReg4. Registrars were trained in data extraction and entry methods, and are periodically monitored by faculty of Emory School of Public Health, IARC, and the MECC. 18

PY - 2010/8

Y1 - 2010/8

N2 - Head and neck cancer (HNC) has been studied in different regions of the world but little is known about its incidence patterns in the Middle East and Egypt. In this study from Egypt's only population-based registry, we analyzed data from 1999 to 2006, to estimate incidence, incidence rate ratios (IRRs) and 95% confidence intervals (CIs) categorized by age, district and subsites. Overall urban incidence of HNC was twice or more that of rural incidence for both males (IRR = 2.59; 95% CI = 2.26, 2.97) and females (IRR = 2.00; 95% CI = 1.64, 2.43). Highest urban-rural difference for males was seen in 40-49 years (IRR = 2.79; 95% CI = 1.92, 4.05) and for females in 30-39 years (IRR = 2.94; 95% CI = 1.60, 5.40). Among subsites, highest incidence among males was for larynx (1.53/105) and among females for gum and mouth (0.48/10 5). Maximum urban-rural difference in males was for paranasal sinus (IRR = 4.66; 95% CI = 1.88, 11.54) and in females for lip (IRR = 8.91; 95% CI = 1.89, 41.98). The study underscores the patterns of HNC incidence in Egypt while indicating the need for future analytical studies investigating specific risk factors of HNC in this population.

AB - Head and neck cancer (HNC) has been studied in different regions of the world but little is known about its incidence patterns in the Middle East and Egypt. In this study from Egypt's only population-based registry, we analyzed data from 1999 to 2006, to estimate incidence, incidence rate ratios (IRRs) and 95% confidence intervals (CIs) categorized by age, district and subsites. Overall urban incidence of HNC was twice or more that of rural incidence for both males (IRR = 2.59; 95% CI = 2.26, 2.97) and females (IRR = 2.00; 95% CI = 1.64, 2.43). Highest urban-rural difference for males was seen in 40-49 years (IRR = 2.79; 95% CI = 1.92, 4.05) and for females in 30-39 years (IRR = 2.94; 95% CI = 1.60, 5.40). Among subsites, highest incidence among males was for larynx (1.53/105) and among females for gum and mouth (0.48/10 5). Maximum urban-rural difference in males was for paranasal sinus (IRR = 4.66; 95% CI = 1.88, 11.54) and in females for lip (IRR = 8.91; 95% CI = 1.89, 41.98). The study underscores the patterns of HNC incidence in Egypt while indicating the need for future analytical studies investigating specific risk factors of HNC in this population.

KW - Africa

KW - Descriptive epidemiology

KW - Egypt

KW - Head and neck cancer

KW - Risk factors

KW - SEER

KW - Urban-rural

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VL - 46

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JO - Oral Oncology

JF - Oral Oncology

IS - 8

ER -

Head and neck cancer in a developing country: A population-based perspective across 8 years

Abstract

Keywords

ASJC Scopus subject areas

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