TY - JOUR
T1 - Health-Related Quality of Life in Patients With a Left Ventricular Assist Device (QOLVAD) Questionnaire
AU - Sandau, Kristin E.
AU - Lee, Christopher S.
AU - Faulkner, Kenneth M.
AU - Pozehl, Bunny
AU - Eckman, Peter
AU - Garberich, Ross
AU - Weaver, Carrie E.
AU - Joseph, Susan M.
AU - Hall, Shelley
AU - Carey, Sandra A.
AU - Chaudhry, Sunit Preet
AU - Schroeder, Sarah E.
AU - Hoffman, Russell O.
AU - Feldman, David
AU - Birati, Edo Y.
AU - Soni, Meshal
AU - Marble, Judith Feighery
AU - Jurgens, Corrine Y.
AU - Hoglund, Barbara
AU - Cowger, Jennifer A.
N1 - Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.
PY - 2021/3/1
Y1 - 2021/3/1
N2 - Background Patients with a left ventricular assist device are a unique and growing population who deserve their own valid, reliable instrument for health-related quality of life. Objective We developed and tested the Health-Related Quality of Life with a Left Ventricular Assist Device (QOLVAD) questionnaire. Methods In a prospective, descriptive study, patients from 7 sites completed the QOLVAD and comparator questionnaires. Construct validity was tested using confirmatory factor analysis. Convergent validity was tested using correlations of QOLVAD scores to well-established measures of subjective health status, depression, anxiety, and meaning/faith. Reliability and test-retest reliability were quantified. Results Patients (n = 213) were 58.7 ± 13.9 years old; 81.0% were male, 73.7% were White, and 48.0% had bridge to transplant. Questionnaires were completed at a median time of 44 weeks post ventricular assist device. The 5 QOLVAD domains had acceptable construct validity (root mean square error of approximation = 0.064, comparative and Tucker-Lewis fit indices > 0.90, weighted root mean square residual = 0.95). The total score and domain-specific scores were significantly correlated with the instruments to which they were compared. Internal consistency reliability was acceptable for all subscales (α =.79-.83) except the cognitive domain (α =.66). Unidimensional reliability for the total score was acceptable (α =.93), as was factor determinacy for multidimensional reliability (0.95). Total test-retest reliability was 0.875 (P <.001). Conclusion Our analysis provided initial support for validity and reliability of the QOLVAD for total score, physical, emotional, social, and meaning/spiritual domains. The QOLVAD has potential in research and clinical settings to guide decision making and referrals; further studies are needed.
AB - Background Patients with a left ventricular assist device are a unique and growing population who deserve their own valid, reliable instrument for health-related quality of life. Objective We developed and tested the Health-Related Quality of Life with a Left Ventricular Assist Device (QOLVAD) questionnaire. Methods In a prospective, descriptive study, patients from 7 sites completed the QOLVAD and comparator questionnaires. Construct validity was tested using confirmatory factor analysis. Convergent validity was tested using correlations of QOLVAD scores to well-established measures of subjective health status, depression, anxiety, and meaning/faith. Reliability and test-retest reliability were quantified. Results Patients (n = 213) were 58.7 ± 13.9 years old; 81.0% were male, 73.7% were White, and 48.0% had bridge to transplant. Questionnaires were completed at a median time of 44 weeks post ventricular assist device. The 5 QOLVAD domains had acceptable construct validity (root mean square error of approximation = 0.064, comparative and Tucker-Lewis fit indices > 0.90, weighted root mean square residual = 0.95). The total score and domain-specific scores were significantly correlated with the instruments to which they were compared. Internal consistency reliability was acceptable for all subscales (α =.79-.83) except the cognitive domain (α =.66). Unidimensional reliability for the total score was acceptable (α =.93), as was factor determinacy for multidimensional reliability (0.95). Total test-retest reliability was 0.875 (P <.001). Conclusion Our analysis provided initial support for validity and reliability of the QOLVAD for total score, physical, emotional, social, and meaning/spiritual domains. The QOLVAD has potential in research and clinical settings to guide decision making and referrals; further studies are needed.
KW - LVAD
KW - cardiac assist device
KW - health-related quality of life
KW - instrument development
KW - quality of life
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U2 - 10.1097/JCN.0000000000000774
DO - 10.1097/JCN.0000000000000774
M3 - Article
C2 - 33306621
AN - SCOPUS:85101923077
SN - 0889-4655
VL - 36
SP - 172
EP - 184
JO - Journal of Cardiovascular Nursing
JF - Journal of Cardiovascular Nursing
IS - 2
ER -