Abstract

Hematopoietic stem cell transplantation has become increasingly important in the treatment of hematologic malignancies over the past 20 years. While it is associated with significant morbidity, it offers the only chance of cure in many circumstances. Autologous and allogeneic transplantation have been used successfully to treat a variety of hematologic malignancies. These 2 approaches offer different risks and benefits which are discussed in this review. Timing of transplantation and selection of patients are also discussed. New innovations in stem cell transplantation including umbilical cord blood and non-myeloablative transplantation are reviewed.

Original languageEnglish (US)
Pages (from-to)61-74
Number of pages14
JournalPanminerva Medica
Volume46
Issue number1
StatePublished - Mar 2004

Keywords

  • Hematopoietic stem cells
  • Hematopoietic stem cells transplantation
  • Stem cells

ASJC Scopus subject areas

  • Medicine(all)

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