Hepatocarcinoma in a Child With the Alagille Syndrome

Stuart S. Kaufman, R. Patrick Wood, B. W. Shaw, Rodney S. Markin, Bruno Gridelli, Jon A. Vanderhoof

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


A child with the Alagille syndrome of intrahepatic bile duct paucity developed hepatocarcinoma. Disabling cirrhosis had rendered this child a suitable candidate for transplantation before the discovery of carcinoma. However, the extension of the tumor outside the liver precluded the performance of this potentially life-saving operation. Serial monitoring of the serum μ-fetoprotein concentration may be of value in the early identification of tumors in pediatric candidates for transplantation.

Original languageEnglish (US)
Pages (from-to)698-700
Number of pages3
JournalAmerican Journal of Diseases of Children
Issue number6
StatePublished - Jun 1987

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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