Hepatocellular carcinoma

Daniel F. Schafer, Michael F. Sorrell

Research output: Contribution to journalReview articlepeer-review

526 Scopus citations


Hepatocellular carcinoma (HCC) for most patients is a terminal complication of chronic inflammatory and fibrotic liver disease. With regrettably few exceptions, treatment is largely palliative, and long-term survival is rare. However, the major causes of HCC worldwide are known and preventable. Hepatitis B and C exist only in man; the viruses have no known non-human reservoirs. Transmission of the viruses can be interrupted by vaccination against hepatitis B virus infection and improvements in medical techniques for hepatitis C, for which no vaccine has yet been developed.

Original languageEnglish (US)
Pages (from-to)1253-1257
Number of pages5
Issue number9160
StatePublished - Apr 10 1999

ASJC Scopus subject areas

  • Medicine(all)


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