Hepatosplenic γ-δ T-Cell Lymphoma: Who Is on Your Speed Dial?

Mridula Krishnan, Matthew Lunning

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Hepatosplenic γ-δ T-cell lymphoma, an exceptionally uncommon subtype of peripheral T-cell lymphomas, commonly presents with advanced-stage disease manifesting with hepatosplenomegaly, cytopenias, and constitutional symptoms. Management of this subset is challenging as a result of the unique presentation and refractory nature to conventional treatment approaches. There is a lack of consensus guidelines for up-front induction strategies, and the role of consolidative autologous or allogeneic stem-cell transplantation is controversial. Prospective studies are lacking, and treatment is often guided by literature on the basis of case series or single-institution studies, lending to expert opinions influencing treatment paradigms.

Original languageEnglish (US)
Pages (from-to)307-312
Number of pages6
JournalJournal of oncology practice
Volume15
Issue number6
DOIs
StatePublished - Jun 1 2019

ASJC Scopus subject areas

  • Oncology
  • Oncology(nursing)
  • Health Policy

Fingerprint Dive into the research topics of 'Hepatosplenic γ-δ T-Cell Lymphoma: Who Is on Your Speed Dial?'. Together they form a unique fingerprint.

  • Cite this