Heritable Congenital Defects

Brian K. Whitlock, Jonathan E. Beever, David J. Steffen

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Heritable congenital defects are being recognized at an increasing rate, but only a few are unequivocally propagated as a result of specific but unrelated trait selection. This chapter describes the fundamentals of report investigations, and morphologic characteristics, mode of inheritance, breeds affected, and availability of specific tests or anatomic hallmarks for select heritable bovine fetal abnormalities. The etiologies of congenital defects in cattle can be divided into heritable, toxic, nutritional, and infectious categories; distinguishing among different causes is essential in the management of the disease but may be challenging. Arthrogryposis multiplex (AM) is a lethal autosomal recessive genetic defect that originated in Angus cattle. Congenital contractural arachnodactyly, or “fawn calf syndrome, " is a non-lethal autosomal recessive genetic defect of Angus cattle. Neuropathic hydrocephalus (“water head”) is a lethal autosomal recessive genetic defect of Angus cattle. At the same time that AM calves were being submitted, calves with hydrocephalus were also submitted.

Original languageEnglish (US)
Title of host publicationBovine Reproduction
Publisherwiley
Pages863-875
Number of pages13
ISBN (Electronic)9781119602484
DOIs
StatePublished - Jan 1 2021

Keywords

  • Anatomic hallmarks
  • Angus cattle
  • Arthrogryposis multiplex
  • Congenital contractural arachnodactyly
  • Heritable bovine fetal abnormalities
  • Heritable congenital defects
  • Morphologic characteristics
  • Neuropathic hydrocephalus

ASJC Scopus subject areas

  • General Veterinary

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