Heterologous pathway engineering

Wei Niu, Jiantao Guo, Steve Van Dien

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations


Heterologous pathways encompass both natural and artificial biosynthetic routes. Expression of a heterologous pathway expands the molecular diversity that can be realized by the host organism. The engineering efforts often benefit from a well-established technological platform of the host. This chapter discusses recent progress and key challenges in implementing heterologous pathways. Major topics include enzyme discovery for artificial pathway assembly, methods for studying and tuning the performance of a pathway, and examples of heterologous pathway engineering.

Original languageEnglish (US)
Title of host publicationMetabolic Engineering for Bioprocess Commercialization
PublisherSpringer International Publishing
Number of pages22
ISBN (Electronic)9783319419664
ISBN (Print)9783319419640
StatePublished - Jan 1 2016


  • Biosynthesis
  • Enzyme
  • Heterologous pathway
  • Metabolic engineering

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Medicine


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