Heterologous pathway engineering

Wei Niu; Jiantao Guo; Steve Van Dien

doi:10.1007/978-3-319-41966-4_3

Heterologous pathway engineering

Wei Niu, Jiantao Guo, Steve Van Dien

Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Scopus citations

Abstract

Heterologous pathways encompass both natural and artificial biosynthetic routes. Expression of a heterologous pathway expands the molecular diversity that can be realized by the host organism. The engineering efforts often benefit from a well-established technological platform of the host. This chapter discusses recent progress and key challenges in implementing heterologous pathways. Major topics include enzyme discovery for artificial pathway assembly, methods for studying and tuning the performance of a pathway, and examples of heterologous pathway engineering.

Original language	English (US)
Title of host publication	Metabolic Engineering for Bioprocess Commercialization
Publisher	Springer International Publishing
Pages	31-52
Number of pages	22
ISBN (Electronic)	9783319419664
ISBN (Print)	9783319419640
DOIs	https://doi.org/10.1007/978-3-319-41966-4_3
State	Published - Jan 1 2016

Keywords

Biosynthesis
Enzyme
Heterologous pathway
Metabolic engineering

ASJC Scopus subject areas

General Agricultural and Biological Sciences
General Medicine

Access to Document

10.1007/978-3-319-41966-4_3

Cite this

@inbook{9e7193d2d0f64b13883af13d0cb03fe0,

title = "Heterologous pathway engineering",

abstract = "Heterologous pathways encompass both natural and artificial biosynthetic routes. Expression of a heterologous pathway expands the molecular diversity that can be realized by the host organism. The engineering efforts often benefit from a well-established technological platform of the host. This chapter discusses recent progress and key challenges in implementing heterologous pathways. Major topics include enzyme discovery for artificial pathway assembly, methods for studying and tuning the performance of a pathway, and examples of heterologous pathway engineering.",

keywords = "Biosynthesis, Enzyme, Heterologous pathway, Metabolic engineering",

author = "Wei Niu and Jiantao Guo and {Van Dien}, Steve",

year = "2016",

month = jan,

day = "1",

doi = "10.1007/978-3-319-41966-4_3",

language = "English (US)",

isbn = "9783319419640",

pages = "31--52",

booktitle = "Metabolic Engineering for Bioprocess Commercialization",

publisher = "Springer International Publishing",

}

TY - CHAP

T1 - Heterologous pathway engineering

AU - Niu, Wei

AU - Guo, Jiantao

AU - Van Dien, Steve

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Heterologous pathways encompass both natural and artificial biosynthetic routes. Expression of a heterologous pathway expands the molecular diversity that can be realized by the host organism. The engineering efforts often benefit from a well-established technological platform of the host. This chapter discusses recent progress and key challenges in implementing heterologous pathways. Major topics include enzyme discovery for artificial pathway assembly, methods for studying and tuning the performance of a pathway, and examples of heterologous pathway engineering.

AB - Heterologous pathways encompass both natural and artificial biosynthetic routes. Expression of a heterologous pathway expands the molecular diversity that can be realized by the host organism. The engineering efforts often benefit from a well-established technological platform of the host. This chapter discusses recent progress and key challenges in implementing heterologous pathways. Major topics include enzyme discovery for artificial pathway assembly, methods for studying and tuning the performance of a pathway, and examples of heterologous pathway engineering.

KW - Biosynthesis

KW - Enzyme

KW - Heterologous pathway

KW - Metabolic engineering

UR - http://www.scopus.com/inward/record.url?scp=85026348209&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85026348209&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-41966-4_3

DO - 10.1007/978-3-319-41966-4_3

M3 - Chapter

AN - SCOPUS:85026348209

SN - 9783319419640

SP - 31

EP - 52

BT - Metabolic Engineering for Bioprocess Commercialization

PB - Springer International Publishing

ER -

Heterologous pathway engineering

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this