Heterologous pathway engineering

Wei Niu, Jiantao Guo, Steve Van Dien

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Heterologous pathways encompass both natural and artificial biosynthetic routes. Expression of a heterologous pathway expands the molecular diversity that can be realized by the host organism. The engineering efforts often benefit from a well-established technological platform of the host. This chapter discusses recent progress and key challenges in implementing heterologous pathways. Major topics include enzyme discovery for artificial pathway assembly, methods for studying and tuning the performance of a pathway, and examples of heterologous pathway engineering.

Original languageEnglish (US)
Title of host publicationMetabolic Engineering for Bioprocess Commercialization
PublisherSpringer International Publishing
Pages31-52
Number of pages22
ISBN (Electronic)9783319419664
ISBN (Print)9783319419640
DOIs
StatePublished - Jan 1 2016

Keywords

  • Biosynthesis
  • Enzyme
  • Heterologous pathway
  • Metabolic engineering

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Medicine(all)

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  • Cite this

    Niu, W., Guo, J., & Van Dien, S. (2016). Heterologous pathway engineering. In Metabolic Engineering for Bioprocess Commercialization (pp. 31-52). Springer International Publishing. https://doi.org/10.1007/978-3-319-41966-4_3