Abstract
Solid-state NMR provides unique possibilities to study insoluble or noncrystalline molecules at the atomic level. High-resolution conditions can be established by employing magic-angle spinning at ultrahigh magnetic fields. We discuss NMR methods that make use of these experimental improvements and allow for the study of multiply or uniformly 13C,15N]-labeled polypeptides and proteins. Recent biophysical applications are reviewed.
Original language | English (US) |
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Pages (from-to) | 858-865 |
Number of pages | 8 |
Journal | Accounts of Chemical Research |
Volume | 36 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2003 |
ASJC Scopus subject areas
- Chemistry(all)