@article{7e90ae611d6e4bf5a8071041980e24f5,
title = "Highly Elastic and Conductive Human-Based Protein Hybrid Hydrogels",
abstract = "The aim of this study is to engineer a biocompatible and stretchable hydrogel with tunable mechanical, electrical, and biological properties based on recombinant human tropoelastin and graphene oxide (GO) nanoparticles. Tropoelastin is the dominant physiological component of elastin, where upon crosslinking it conveys both elasticity and biological activity. The study uses GO nanoparticles to form conductive and elastomeric methacryloyl-substituted tropoelastin (MeTro)/GO hybrid hydrogels. GO is utilized due to its flexibility, biocompatibility, and ease of dispersion in aqueous solutions.",
keywords = "cardiac tissue engineering, elasticity, graphene oxides, hydrogels, tropoelastins",
author = "Nasim Annabi and Shin, {Su Ryon} and Ali Tamayol and Mario Miscuglio and Bakooshli, {Mohsen Afshar} and Alexander Assmann and Pooria Mostafalu and Sun, {Jeong Yun} and Suzanne Mithieux and Louis Cheung and Xiaowu Tang and Weiss, {Anthony S.} and Ali Khademhosseini",
note = "Funding Information: N.A. and S.R.S. contributed equally to this work. A.A. acknowledges postdoctoral funding from the German Heart Foundation, Frankfurt, Germany (S/04/12). A.K. acknowledges funding from the National Science Foundation (EFRI-1240443), ONR PECASE Award, IMMODGEL (602694), and the National Institutes of Health (EB012597, AR057837, DE021468, HL099073, AI105024, and AR063745). ASW acknowledges funding from the NIH (EB014283), the Australian Research Council, and National Health and Medical Research Council (NHMRC). N.A. acknowledges a CJ Martin Fellowship from the NHMRC. The Animal Experimentation Protocol used to obtain the results presented in this study was approved by the Harvard Medical Area Standing Committee on Animals on 10.11.2013.",
year = "2016",
doi = "10.1002/adma.201503255",
language = "English (US)",
volume = "28",
pages = "40--49",
journal = "Advanced Materials",
issn = "0935-9648",
publisher = "Wiley-VCH Verlag",
number = "1",
}