Hippocampal Transections for Epilepsy

Arun Angelo Patil, Andrea Jennifer Chamczuk, Richard V. Andrews

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.

Original languageEnglish (US)
Pages (from-to)19-25
Number of pages7
JournalNeurosurgery Clinics of North America
Volume27
Issue number1
DOIs
StatePublished - Jan 1 2016

Keywords

  • Long-term outcome
  • Multiple hippocampal transection
  • Temporal lobe epilepsy
  • Verbal memory

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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