Hippocampal Transections for Epilepsy

Arun Angelo Patil; Andrea Jennifer Chamczuk; Richard V. Andrews

doi:10.1016/j.nec.2015.08.013

Hippocampal Transections for Epilepsy

Arun Angelo Patil, Andrea Jennifer Chamczuk, Richard V. Andrews

Neurosurgery

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.

Original language	English (US)
Pages (from-to)	19-25
Number of pages	7
Journal	Neurosurgery Clinics of North America
Volume	27
Issue number	1
DOIs	https://doi.org/10.1016/j.nec.2015.08.013
State	Published - Jan 1 2016

Keywords

Long-term outcome
Multiple hippocampal transection
Temporal lobe epilepsy
Verbal memory

ASJC Scopus subject areas

Surgery
Clinical Neurology

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title = "Hippocampal Transections for Epilepsy",

abstract = "Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.",

keywords = "Long-term outcome, Multiple hippocampal transection, Temporal lobe epilepsy, Verbal memory",

author = "Patil, {Arun Angelo} and Chamczuk, {Andrea Jennifer} and Andrews, {Richard V.}",

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T1 - Hippocampal Transections for Epilepsy

AU - Patil, Arun Angelo

AU - Chamczuk, Andrea Jennifer

AU - Andrews, Richard V.

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N2 - Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.

AB - Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.

KW - Long-term outcome

KW - Multiple hippocampal transection

KW - Temporal lobe epilepsy

KW - Verbal memory

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JO - Neurosurgery Clinics of North America

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ER -

Hippocampal Transections for Epilepsy

Abstract

Keywords

ASJC Scopus subject areas

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