Host cell functions in vesicular stomatitis virus replication

Phat X. Dinh, Anshuman Das, Asit K. Pattnaik

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Vesicular stomatitis virus (VSV), the prototypic rhabdovirus, has been used as an excellent paradigm for understanding the mechanisms of virus replication, pathogenesis, host response to virus infection and also for myriads of studies on cellular and molecular biology. Biochemical studies as well as high-throughput genomics, proteomics, and chemical approaches have revealed a plethora of cellular factors and pathways that regulate replication of VSV. These factors include those that support virus replication and also those that restrict its replication. This chapter discusses the role(s) of many of these host cell factors and pathways involved in VSV replication. Although mechanistic understanding of the roles of some of these factors in VSV replication has been obtained, the roles of many others need to be investigated for a better understanding of the virus-host cell interactions.

Original languageEnglish (US)
Title of host publicationBiology and Pathogenesis of Rhabdo- and Filoviruses
PublisherWorld Scientific Publishing Co.
Number of pages33
ISBN (Electronic)9789814635349
ISBN (Print)9789814635332
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Medicine(all)


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