Human herpesvirus 6 infection and Kawasaki disease

M. Okano; J. Luka; G. M. Thiele; Y. Sakiyama; S. Matsumoto; D. T. Purtilo

doi:10.1128/jcm.27.10.2379-2380.1989

Human herpesvirus 6 infection and Kawasaki disease

M. Okano, J. Luka, G. M. Thiele, Y. Sakiyama, S. Matsumoto, D. T. Purtilo

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Abstract

Eighteen of a total of 22 serum specimens (81.8%) from patients with Kawasaki disease were positive for immunoglobulin G or M antibodies to human herpesvirus 6, whereas 10 of 16 age- and sex-matched healthy controls (62.5%) were seropositive. Additionally, increased geometric mean antibody titers of immunoglobulin G were shown in these patients. These results suggest that the status of human herpesvirus 6 infection may be a reflection of the immunologic alterations that are associated with Kawasaki disease.

Original language	English (US)
Pages (from-to)	2379-2380
Number of pages	2
Journal	Journal of clinical microbiology
Volume	27
Issue number	10
DOIs	https://doi.org/10.1128/jcm.27.10.2379-2380.1989
State	Published - 1989

ASJC Scopus subject areas

Microbiology (medical)

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10.1128/jcm.27.10.2379-2380.1989

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AU - Okano, M.

AU - Luka, J.

AU - Thiele, G. M.

AU - Sakiyama, Y.

AU - Matsumoto, S.

AU - Purtilo, D. T.

PY - 1989

Y1 - 1989

N2 - Eighteen of a total of 22 serum specimens (81.8%) from patients with Kawasaki disease were positive for immunoglobulin G or M antibodies to human herpesvirus 6, whereas 10 of 16 age- and sex-matched healthy controls (62.5%) were seropositive. Additionally, increased geometric mean antibody titers of immunoglobulin G were shown in these patients. These results suggest that the status of human herpesvirus 6 infection may be a reflection of the immunologic alterations that are associated with Kawasaki disease.

AB - Eighteen of a total of 22 serum specimens (81.8%) from patients with Kawasaki disease were positive for immunoglobulin G or M antibodies to human herpesvirus 6, whereas 10 of 16 age- and sex-matched healthy controls (62.5%) were seropositive. Additionally, increased geometric mean antibody titers of immunoglobulin G were shown in these patients. These results suggest that the status of human herpesvirus 6 infection may be a reflection of the immunologic alterations that are associated with Kawasaki disease.

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Human herpesvirus 6 infection and Kawasaki disease

Abstract

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