Hydrogel based dermal patch with integrated flexible electronics for on demand drug delivery

S. Bagherifard, A. Tamayol, M. Comotto, P. Mostafalu, M. Akbari, N. Annabi, M. Ghaderi, S. Sonkusale, M. Guagliano, M. R. Dokmeci, A. Khademhosseini

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

It is now widely accepted that the incorporation of growth factors can improve the healing process of chronic wounds. In this paper we combined thermo-responsive drug microcarriers and flexible electronics to create a wound dressing capable of on demand drug delivery. Monodisperse thermo-responsive micoparticles containing active molecules were fabricated using a microfluidic system and were embedded inside a hydrogel. A miniaturized closed-loop electrical system with a flexible heater and temperature sensor was used to heat up the hydrogel and maintain its temperature during the release.

Original languageEnglish (US)
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages2532-2533
Number of pages2
ISBN (Electronic)9780979806476
StatePublished - Jan 1 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014Oct 30 2014

Publication series

Name18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period10/26/1410/30/14

Keywords

  • Drug delivery
  • Microfluidics
  • Thermo sensitivity
  • Wound patch

ASJC Scopus subject areas

  • Control and Systems Engineering

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  • Cite this

    Bagherifard, S., Tamayol, A., Comotto, M., Mostafalu, P., Akbari, M., Annabi, N., Ghaderi, M., Sonkusale, S., Guagliano, M., Dokmeci, M. R., & Khademhosseini, A. (2014). Hydrogel based dermal patch with integrated flexible electronics for on demand drug delivery. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 2532-2533). (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014). Chemical and Biological Microsystems Society.