Hypokalemic Quadriparesis Secondary to Abuse of Cocaine and Heroin

Rajesh Shrestha; Vijaya Raj Bhatt; Ranjit Kumar Chaudhary; Rachana Sedhai; Shiavax Cowasji

Hypokalemic Quadriparesis Secondary to Abuse of Cocaine and Heroin

Rajesh Shrestha, Vijaya Raj Bhatt, Ranjit Kumar Chaudhary, Rachana Sedhai, Shiavax Cowasji

Research output: Contribution to journal › Article › peer-review

Abstract

Low plasma potassium level can cause muscle weakness, lassitude, constipation as well as rhabdomyolysis and arrhythmias, when severe. In muscle, low plasma potassium increases resting membrane potential (hyperpolarization) of myocytes that tend to make muscle more refractory to excitation, leading to muscle weakness. Hypokalemia can be associated with a myriad of causes including drugs of abuse. We present a case of hypokalemia and muscle weakness following use of cocaine and heroin.

Original language	English (US)
Pages (from-to)	32-33
Number of pages	2
Journal	Rhode Island medical journal (2013)
Volume	98
Issue number	3
State	Published - Mar 3 2015

Keywords

cocaine
hypokalemia
muscle weakness
quadriparesis

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "Hypokalemic Quadriparesis Secondary to Abuse of Cocaine and Heroin",

abstract = "Low plasma potassium level can cause muscle weakness, lassitude, constipation as well as rhabdomyolysis and arrhythmias, when severe. In muscle, low plasma potassium increases resting membrane potential (hyperpolarization) of myocytes that tend to make muscle more refractory to excitation, leading to muscle weakness. Hypokalemia can be associated with a myriad of causes including drugs of abuse. We present a case of hypokalemia and muscle weakness following use of cocaine and heroin.",

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AU - Sedhai, Rachana

AU - Cowasji, Shiavax

PY - 2015/3/3

Y1 - 2015/3/3

N2 - Low plasma potassium level can cause muscle weakness, lassitude, constipation as well as rhabdomyolysis and arrhythmias, when severe. In muscle, low plasma potassium increases resting membrane potential (hyperpolarization) of myocytes that tend to make muscle more refractory to excitation, leading to muscle weakness. Hypokalemia can be associated with a myriad of causes including drugs of abuse. We present a case of hypokalemia and muscle weakness following use of cocaine and heroin.

AB - Low plasma potassium level can cause muscle weakness, lassitude, constipation as well as rhabdomyolysis and arrhythmias, when severe. In muscle, low plasma potassium increases resting membrane potential (hyperpolarization) of myocytes that tend to make muscle more refractory to excitation, leading to muscle weakness. Hypokalemia can be associated with a myriad of causes including drugs of abuse. We present a case of hypokalemia and muscle weakness following use of cocaine and heroin.

KW - cocaine

KW - hypokalemia

KW - muscle weakness

KW - quadriparesis

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ER -

Hypokalemic Quadriparesis Secondary to Abuse of Cocaine and Heroin

Abstract

Keywords

ASJC Scopus subject areas

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