Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interaction

Lea Cunningham, Steven Finckbeiner, R. Katherine Hyde, Noel Southall, Juan Marugan, Venkat R.K. Yedavalli, Seameen Jean Dehdashti, William C. Reinhold, Lemlem Alemu, Ling Zhao, Jing Ruey Joanna Yeh, Raman Sood, Yves Pommier, Christopher P. Austin, Kuan Teh Jeang, Wei Zheng, Paul Liu

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Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology

Medicine and Dentistry