TY - JOUR
T1 - Impact of multiple intubation attempts on adverse tracheal intubation associated events in neonates
T2 - a report from the NEAR4NEOS
AU - National Emergency Airway Registry for Neonates (NEAR4NEOS)
AU - Singh, Neetu
AU - Sawyer, Taylor
AU - Johnston, Lindsay C.
AU - Herrick, Heidi M.
AU - Moussa, Ahmed
AU - Zenge, Jeanne
AU - Jung, Philipp
AU - DeMeo, Stephen
AU - Glass, Kristen
AU - Howlett, Alexandra
AU - Shults, Justine
AU - Barry, James
AU - Brei, Brianna K.
AU - Kim, Jae H.
AU - Quek, Bin Huey
AU - Tingay, David
AU - Mehrem, Ayman Abou
AU - Napolitano, Natalie
AU - Nishisaki, Akira
AU - Foglia, Elizabeth E.
N1 - Funding Information:
This research was supported by NICHD R21 HD089151. Akira Nishisaki was supported by NICHD R21 HD089151 and AHRQ R18HS024511. EEF was supported by NICHD K23HD084727 and is a consultant for Medtronic. Natalie Napolitano was supported by NICHD R21 HD 089151 and AHRQ R18HS024511 and have research and/or consulting relationships with Drager, Actuated Medical, Smiths Medical, and VERO-Biotech. DGT is supported by a National Health and Medical Research Council (Australia) Investigator (Grant ID 2008212) and the Victorian Government Operational Infrastructure Support Program (Melbourne, Australia).
Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Nature America, Inc.
PY - 2022/9
Y1 - 2022/9
N2 - Objective: To determine the relationship between number of attempts and adverse events during neonatal intubation. Study design: A retrospective study of prospectively collected data of intubations in the delivery room and NICU from the National Emergency Airway Registry for Neonates (NEAR4NEOS) in 17 academic centers from 1/2016 to 12/2019. We examined the association between tracheal intubation attempts [1, 2, and ≥3 (multiple attempts)] and clinical adverse outcomes (any tracheal intubation associated events (TIAE), severe TIAE, and severe oxygen desaturation). Results: Of 7708 intubations, 1474 (22%) required ≥3 attempts. Patient, provider, and practice factors were associated with higher TI attempts. Increasing intubation attempts was independently associated with a higher risk for TIAE. The adjusted odds ratio for TIAE and severe oxygen desaturation were significantly higher in TIs with 2 and ≥3 attempts than with one attempt. Conclusion: The risk of adverse safety events during intubation increases with the number of intubation attempts.
AB - Objective: To determine the relationship between number of attempts and adverse events during neonatal intubation. Study design: A retrospective study of prospectively collected data of intubations in the delivery room and NICU from the National Emergency Airway Registry for Neonates (NEAR4NEOS) in 17 academic centers from 1/2016 to 12/2019. We examined the association between tracheal intubation attempts [1, 2, and ≥3 (multiple attempts)] and clinical adverse outcomes (any tracheal intubation associated events (TIAE), severe TIAE, and severe oxygen desaturation). Results: Of 7708 intubations, 1474 (22%) required ≥3 attempts. Patient, provider, and practice factors were associated with higher TI attempts. Increasing intubation attempts was independently associated with a higher risk for TIAE. The adjusted odds ratio for TIAE and severe oxygen desaturation were significantly higher in TIs with 2 and ≥3 attempts than with one attempt. Conclusion: The risk of adverse safety events during intubation increases with the number of intubation attempts.
UR - http://www.scopus.com/inward/record.url?scp=85136288792&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85136288792&partnerID=8YFLogxK
U2 - 10.1038/s41372-022-01484-5
DO - 10.1038/s41372-022-01484-5
M3 - Article
C2 - 35982243
AN - SCOPUS:85136288792
VL - 42
SP - 1221
EP - 1227
JO - Journal of Perinatology
JF - Journal of Perinatology
SN - 0743-8346
IS - 9
ER -