Improved arene fluorination methodology for I(III) salts

Bijia Wang; Linlin Qin; Kiel D. Neumann; Shriharsha Uppaluri; Ronald L. Cerny; Stephen G. DiMagno

doi:10.1021/ol101154h

Improved arene fluorination methodology for I(III) salts

Bijia Wang, Linlin Qin, Kiel D. Neumann, Shriharsha Uppaluri, Ronald L. Cerny, Stephen G. DiMagno

Research output: Contribution to journal › Article › peer-review

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Abstract

(Equation Presented). The use of low polarity aromatic solvents (benzene or toluene) and/or the removal of inorganic salts results in dramatically improved yields of fluorinated arenes from diaryliodonium salts. This methodology is shown to "scale down" to the conditions used typically for radiotracer synthesis.

Original language	English (US)
Pages (from-to)	3352-3355
Number of pages	4
Journal	Organic Letters
Volume	12
Issue number	15
DOIs	https://doi.org/10.1021/ol101154h
State	Published - Aug 6 2010

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol101154h

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title = "Improved arene fluorination methodology for I(III) salts",

abstract = "(Equation Presented). The use of low polarity aromatic solvents (benzene or toluene) and/or the removal of inorganic salts results in dramatically improved yields of fluorinated arenes from diaryliodonium salts. This methodology is shown to {"}scale down{"} to the conditions used typically for radiotracer synthesis.",

author = "Bijia Wang and Linlin Qin and Neumann, {Kiel D.} and Shriharsha Uppaluri and Cerny, {Ronald L.} and DiMagno, {Stephen G.}",

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T1 - Improved arene fluorination methodology for I(III) salts

AU - Wang, Bijia

AU - Qin, Linlin

AU - Neumann, Kiel D.

AU - Uppaluri, Shriharsha

AU - Cerny, Ronald L.

AU - DiMagno, Stephen G.

PY - 2010/8/6

Y1 - 2010/8/6

N2 - (Equation Presented). The use of low polarity aromatic solvents (benzene or toluene) and/or the removal of inorganic salts results in dramatically improved yields of fluorinated arenes from diaryliodonium salts. This methodology is shown to "scale down" to the conditions used typically for radiotracer synthesis.

AB - (Equation Presented). The use of low polarity aromatic solvents (benzene or toluene) and/or the removal of inorganic salts results in dramatically improved yields of fluorinated arenes from diaryliodonium salts. This methodology is shown to "scale down" to the conditions used typically for radiotracer synthesis.

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JO - Organic Letters

JF - Organic Letters

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Improved arene fluorination methodology for I(III) salts

Abstract

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