Improved method for the synthesis of phosphatidylcholines

G. S. Harbison, R. G. Griffin

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


An improved method for the synthesis of phosphatidylcholines from phosphatidic acid and choline is described. The technique utilizes the tetraphenylborate salt of choline together with the condensing agent 2,4,6-triisopropylbenzenesulfonyl chloride. The yields in the reaction are consistently in the range 70-75%.

Original languageEnglish (US)
Pages (from-to)1140-1142
Number of pages3
JournalJournal of Lipid Research
Issue number10
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Cell Biology


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