Abstract
(Chemical Equation Presented) Combinatorial screening of five catalyst precursors and nine ligands with three substituted aniline trapping reagents uncovered a catalyst system that promotes efficient palladium-catalyzed cyclization-trapping with a series of substituted anilines of varying steric and electronic character. The results of the parallel optimization study illustrate the interdependency of the key reaction variables.
Original language | English (US) |
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Pages (from-to) | 3099-3102 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 6 |
Issue number | 18 |
DOIs | |
State | Published - Sep 2 2004 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry