Improving the lives of patients with medically refractory epilepsy by electrical stimulation of the nervous system

Jerome V. Murphy; Arun Angelo Patil

doi:10.1586/17434440.2.2.175

Improving the lives of patients with medically refractory epilepsy by electrical stimulation of the nervous system

Jerome V. Murphy, Arun Angelo Patil

Neurosurgery

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

Vagal nerve stimulation proved effective in animal models of epilepsy, and in open and double-blinded trials, in over 450 patients. Seizure reduction improved for at least 2 years. Almost 60% of treated patients achieve at least a 50% reduction in seizure frequency. Other advantages include termination of a seizure and improved alertness. Benefits were demonstrated in children, partial and generalized epilepsies, and in specific neurologic syndromes.

Original language	English (US)
Pages (from-to)	175-189
Number of pages	15
Journal	Expert Review of Medical Devices
Volume	2
Issue number	2
DOIs	https://doi.org/10.1586/17434440.2.2.175
State	Published - Mar 2005

Keywords

Deep brain stimulation
Refractory epilepsy
Vagal nerve stimulation

ASJC Scopus subject areas

Surgery
Biomedical Engineering

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10.1586/17434440.2.2.175

Cite this

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abstract = "Vagal nerve stimulation proved effective in animal models of epilepsy, and in open and double-blinded trials, in over 450 patients. Seizure reduction improved for at least 2 years. Almost 60% of treated patients achieve at least a 50% reduction in seizure frequency. Other advantages include termination of a seizure and improved alertness. Benefits were demonstrated in children, partial and generalized epilepsies, and in specific neurologic syndromes.",

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AB - Vagal nerve stimulation proved effective in animal models of epilepsy, and in open and double-blinded trials, in over 450 patients. Seizure reduction improved for at least 2 years. Almost 60% of treated patients achieve at least a 50% reduction in seizure frequency. Other advantages include termination of a seizure and improved alertness. Benefits were demonstrated in children, partial and generalized epilepsies, and in specific neurologic syndromes.

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Improving the lives of patients with medically refractory epilepsy by electrical stimulation of the nervous system

Abstract

Keywords

ASJC Scopus subject areas

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