@article{723bc621258a4af388457959a0923524,
title = "Improving the Pharmacologic Management of Pain in Older Adults: Identifying the Research Gaps and Methods to Address Them",
abstract = "Objective. There has been a growing recognition of the need for better pharmacologic management of chronic pain among older adults. To address this need, the National Institutes of Health Pain Consortium sponsored an {"}Expert Panel Discussion on the Pharmacological Management of Chronic Pain in Older Adults{"} conference in September 2010 to identify research gaps and strategies to address them. Specific emphasis was placed on ascertaining gaps regarding use of opioid and nonsteroidal anti-inflammatory medications because of continued uncertainties regarding their risks and benefits. Design. Eighteen panel members provided oral presentations; each was followed by a multidisciplinary panel discussion. Meeting transcripts and panelists' slide presentations were reviewed to identify the gaps and the types of studies and research methods panelists suggested could best address them. Results. Fifteen gaps were identified in the areas of treatment (e.g., uncertainty regarding the long-term safety and efficacy of commonly prescribed analgesics), epidemiology (e.g., lack of knowledge regarding the course of common pain syndromes), and implementation (e.g., limited understanding of optimal strategies to translate evidence-based pain treatments into practice). Analyses of data from electronic health care databases, observational cohort studies, and ongoing cohort studies (augmented with pain and other relevant outcomes measures) were felt to be practical methods for building an age-appropriate evidence base to improve the pharmacologic management of pain in later life. Conclusion. Addressing the gaps presented in the current report was judged by the panel to have substantial potential to improve the health and well-being of older adults with chronic pain. Wiley Periodicals, Inc.",
keywords = "Analgesic Use, Chronic Noncancer Pain, Older Adults",
author = "Reid, {M. Cary} and Bennett, {David A.} and Chen, {Wen G.} and Eldadah, {Basil A.} and Farrar, {John T.} and Bruce Ferrell and Gallagher, {Rollin M.} and Hanlon, {Joseph T.} and Keela Herr and Horn, {Susan D.} and Inturrisi, {Charles E.} and Salma Lemtouni and Lin, {Yu Woody} and Kaleb Michaud and Morrison, {R. Sean} and Tuhina Neogi and Porter, {Linda L.} and Solomon, {Daniel H.} and {Von Korff}, Michael and Karen Weiss and James Witter and Zacharoff, {Kevin L.}",
note = "Funding Information: The authors would like to acknowledge the participation of all the conference attendees, who are listed in Appendix A . Dr. Reid was supported by an Edward R. Roybal Center for Translational Research on Aging Award ( P30 AG22845 ) provided by the NIA. Dr. Bennett was supported by NIA grants P30AG10161, R01AG15819, and R01AG17917 . Dr. Farrar was supported by a grant from the National Center for Research Resources ( UL1RR024134 ). Dr. Hanlon was supported by National Institute of Aging grants ( P30AG024827, T32AG021885, K07AG033174, R01AG034056, R56AG027017, U01AG012553 ), a National Institute of Mental Health grant ( R34MH082682 ), a National Institute of Nursing Research grant ( R01NR010135 ), AHRQ grants ( R01HS017695, R01HS018721, K12HS019461 ), and a VA Health Services Research grant ( IIR-06-062 ). Dr. Herr was supported by grants from the National Cancer Institute ( R01CA115363 ) and National Institute of Nursing Research ( T32NR011147 ). Drs. Horn and Inturrisi were supported by American Recovery and Reinvestment Act (ARRA) grant RC2DA028928 from NIDA. Dr. Michaud was supported by an ARRA grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) ( RC1AR058601 ). Dr. Neogi was supported by a grant from the NIAMS ( K23AR055127 ). Dr. Morrison was supported by grants from the NIA ( P30AG028741, K24AG022345, and R01AG030141 ). Dr. Solomon was supported by a grant from the NIAMS ( K24AR055989 ). Dr. Von Korff was supported by grants from the NIDA ( R01DA022557 ) and the NIA ( R01AG034181 ). Funding Information: The electronic health care databases of health plans in the Health Maintenance Organization (HMO) Research Network are accessed through research centers affiliated with each of the plans, generally through collaborative research with investigators in health plan research centers. Each research center has its own procedures for considering research proposals using health plan data, including human subjects protection review. The research centers in the HMO Research Network have developed a virtual data warehouse to facilitate analyses of data across multiple plans, employing common data definitions and algorithms that can be applied across health plan data sets. There are a variety of research consortia funded by the federal agencies that use HMO Research Network data through diverse funding mechanisms. These include: the Center for Education and Research on Therapeutics (funded by the AHRQ); the Vaccine Safety Datalink (CDC); the Mini-Sentinel network (FDA); cancer, cardiovascular disease, and mental health research networks (NCI, NHLBI, NIMH); and the NIH-HMO Collaboratory (NIH), among others. ",
year = "2011",
month = sep,
doi = "10.1111/j.1526-4637.2011.01211.x",
language = "English (US)",
volume = "12",
pages = "1336--1357",
journal = "Pain Medicine",
issn = "1526-2375",
publisher = "VICER Publishing",
number = "9",
}