In vivo microbubble cavitation imaging

François Vignon, William Shi, Jinjin Liu, Feng Xie, Shunji Gao, Lucas Drvol, Johl Lof, Carr Everbach, Thomas Porter, Jeff Powers

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Stroke is the second cause of death and a leading cause of disability worldwide. Less than 5% of ischemic stroke patients receive the state-of-the art treatment of a thrombolytic drug tPA, and only about 10% of these gain additional benefit from it. Ultrasound (US)-induced microbubble (MB) cavitation has been shown to enhance the efficacy of the tPA drug, and dissolve clots without tPA. Such a sonothrombolysis (STL) treatment requires monitoring and control of MB cavitation to ensure its reproducible efficacy and safety.

Original languageEnglish (US)
Title of host publication2011 IEEE International Ultrasonics Symposium, IUS 2011
Pages927-930
Number of pages4
DOIs
StatePublished - 2011
Event2011 IEEE International Ultrasonics Symposium, IUS 2011 - Orlando, FL, United States
Duration: Oct 18 2011Oct 21 2011

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2011 IEEE International Ultrasonics Symposium, IUS 2011
CountryUnited States
CityOrlando, FL
Period10/18/1110/21/11

Keywords

  • Cavitation
  • Cavitation monitoring
  • Contrast Agents
  • Image-guided therapy
  • Microbubbles
  • Sonothrombolysis
  • Stroke

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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  • Cite this

    Vignon, F., Shi, W., Liu, J., Xie, F., Gao, S., Drvol, L., Lof, J., Everbach, C., Porter, T., & Powers, J. (2011). In vivo microbubble cavitation imaging. In 2011 IEEE International Ultrasonics Symposium, IUS 2011 (pp. 927-930). [6293554] (IEEE International Ultrasonics Symposium, IUS). https://doi.org/10.1109/ULTSYM.2011.0227