In vivo microbubble cavitation imaging

François Vignon; William Shi; Jinjin Liu; Feng Xie; Shunji Gao; Lucas Drvol; Johl Lof; Carr Everbach; Thomas Porter; Jeff Powers

doi:10.1109/ULTSYM.2011.0227

In vivo microbubble cavitation imaging

François Vignon, William Shi, Jinjin Liu, Feng Xie, Shunji Gao, Lucas Drvol, Johl Lof, Carr Everbach, Thomas Porter, Jeff Powers

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Stroke is the second cause of death and a leading cause of disability worldwide. Less than 5% of ischemic stroke patients receive the state-of-the art treatment of a thrombolytic drug tPA, and only about 10% of these gain additional benefit from it. Ultrasound (US)-induced microbubble (MB) cavitation has been shown to enhance the efficacy of the tPA drug, and dissolve clots without tPA. Such a sonothrombolysis (STL) treatment requires monitoring and control of MB cavitation to ensure its reproducible efficacy and safety.

Original language	English (US)
Title of host publication	2011 IEEE International Ultrasonics Symposium, IUS 2011
Pages	927-930
Number of pages	4
DOIs	https://doi.org/10.1109/ULTSYM.2011.0227
State	Published - 2011
Event	2011 IEEE International Ultrasonics Symposium, IUS 2011 - Orlando, FL, United States Duration: Oct 18 2011 → Oct 21 2011

Publication series

Name	IEEE International Ultrasonics Symposium, IUS
ISSN (Print)	1948-5719
ISSN (Electronic)	1948-5727

Conference

Conference	2011 IEEE International Ultrasonics Symposium, IUS 2011
Country/Territory	United States
City	Orlando, FL
Period	10/18/11 → 10/21/11

Keywords

Cavitation
Cavitation monitoring
Contrast Agents
Image-guided therapy
Microbubbles
Sonothrombolysis
Stroke

ASJC Scopus subject areas

Acoustics and Ultrasonics

Access to Document

10.1109/ULTSYM.2011.0227

Cite this

Vignon, F, Shi, W, Liu, J, Xie, F, Gao, S, Drvol, L, Lof, J, Everbach, C, Porter, T & Powers, J 2011, In vivo microbubble cavitation imaging. in 2011 IEEE International Ultrasonics Symposium, IUS 2011., 6293554, IEEE International Ultrasonics Symposium, IUS, pp. 927-930, 2011 IEEE International Ultrasonics Symposium, IUS 2011, Orlando, FL, United States, 10/18/11. https://doi.org/10.1109/ULTSYM.2011.0227

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title = "In vivo microbubble cavitation imaging",

abstract = "Stroke is the second cause of death and a leading cause of disability worldwide. Less than 5% of ischemic stroke patients receive the state-of-the art treatment of a thrombolytic drug tPA, and only about 10% of these gain additional benefit from it. Ultrasound (US)-induced microbubble (MB) cavitation has been shown to enhance the efficacy of the tPA drug, and dissolve clots without tPA. Such a sonothrombolysis (STL) treatment requires monitoring and control of MB cavitation to ensure its reproducible efficacy and safety.",

keywords = "Cavitation, Cavitation monitoring, Contrast Agents, Image-guided therapy, Microbubbles, Sonothrombolysis, Stroke",

author = "Fran{\c c}ois Vignon and William Shi and Jinjin Liu and Feng Xie and Shunji Gao and Lucas Drvol and Johl Lof and Carr Everbach and Thomas Porter and Jeff Powers",

year = "2011",

doi = "10.1109/ULTSYM.2011.0227",

language = "English (US)",

isbn = "9781457712531",

series = "IEEE International Ultrasonics Symposium, IUS",

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booktitle = "2011 IEEE International Ultrasonics Symposium, IUS 2011",

note = "2011 IEEE International Ultrasonics Symposium, IUS 2011 ; Conference date: 18-10-2011 Through 21-10-2011",

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T1 - In vivo microbubble cavitation imaging

AU - Vignon, François

AU - Shi, William

AU - Liu, Jinjin

AU - Xie, Feng

AU - Gao, Shunji

AU - Drvol, Lucas

AU - Lof, Johl

AU - Everbach, Carr

AU - Porter, Thomas

AU - Powers, Jeff

PY - 2011

Y1 - 2011

N2 - Stroke is the second cause of death and a leading cause of disability worldwide. Less than 5% of ischemic stroke patients receive the state-of-the art treatment of a thrombolytic drug tPA, and only about 10% of these gain additional benefit from it. Ultrasound (US)-induced microbubble (MB) cavitation has been shown to enhance the efficacy of the tPA drug, and dissolve clots without tPA. Such a sonothrombolysis (STL) treatment requires monitoring and control of MB cavitation to ensure its reproducible efficacy and safety.

AB - Stroke is the second cause of death and a leading cause of disability worldwide. Less than 5% of ischemic stroke patients receive the state-of-the art treatment of a thrombolytic drug tPA, and only about 10% of these gain additional benefit from it. Ultrasound (US)-induced microbubble (MB) cavitation has been shown to enhance the efficacy of the tPA drug, and dissolve clots without tPA. Such a sonothrombolysis (STL) treatment requires monitoring and control of MB cavitation to ensure its reproducible efficacy and safety.

KW - Cavitation

KW - Cavitation monitoring

KW - Contrast Agents

KW - Image-guided therapy

KW - Microbubbles

KW - Sonothrombolysis

KW - Stroke

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U2 - 10.1109/ULTSYM.2011.0227

DO - 10.1109/ULTSYM.2011.0227

M3 - Conference contribution

AN - SCOPUS:84869053050

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T3 - IEEE International Ultrasonics Symposium, IUS

SP - 927

EP - 930

BT - 2011 IEEE International Ultrasonics Symposium, IUS 2011

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Y2 - 18 October 2011 through 21 October 2011

ER -

In vivo microbubble cavitation imaging

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

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