TY - JOUR
T1 - Increasing Burden of Complex Multimorbidity Across Gradients of Cognitive Impairment
AU - Koroukian, Siran M.
AU - Schiltz, Nicholas K.
AU - Warner, David F.
AU - Stange, Kurt C.
AU - Smyth, Kathleen A.
N1 - Funding Information:
The authors disclosed receipt of the following financial support for the research and/or authorship of this article: This publication is a product of the Prevention Research Center for Healthy Neighborhoods at Case Western Reserve University, supported by Cooperative Agreement Cooperative Agreement Number, SIP 14-004, U48 DP005030-01S3, under the Health Promotion and Disease Prevention Research Centers Program, funded by the Centers for Disease Control and Prevention. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention or the Department of Health and Human Services. Some of the authors were also supported by a grant from the Agency for Healthcare Research and Quality (R21 HS023113) and the Clinical and Translational Science Collaborative of Cleveland (UL1TR000439) from the National Center for Advancing Translational Sciences (NCATS) component of the National Institutes of Health and NIH roadmap for Medical Research. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIH.
Publisher Copyright:
© SAGE Publications.
PY - 2017/11/1
Y1 - 2017/11/1
N2 - Introduction: This study evaluates the burden of multimorbidity (MM) across gradients of cognitive impairment (CI). Methods: Using data from the 2010 Health and Retirement Study, we identified individuals with no CI, mild CI, and moderate/severe CI. In addition, we adopted an expansive definition of complex MM by accounting for the occurrence and co-occurrence of chronic conditions, functional limitations, and geriatric syndromes. Results: In a sample of 18 913 participants (weighted n = 87.5 million), 1.93% and 1.84% presented with mild and moderate/severe CI, respectively. The prevalence of most conditions constituting complex MM increased markedly across the spectrum of CI. Further, the percentage of individuals presenting with 10 or more conditions was 19.9%, 39.3%, and 71.3% among those with no CI, mild CI, and moderate/severe CI, respectively. Discussion: Greater CI is strongly associated with increased burden of complex MM. Detailed characterization of MM across CI gradients will help identify opportunities for health care improvement.
AB - Introduction: This study evaluates the burden of multimorbidity (MM) across gradients of cognitive impairment (CI). Methods: Using data from the 2010 Health and Retirement Study, we identified individuals with no CI, mild CI, and moderate/severe CI. In addition, we adopted an expansive definition of complex MM by accounting for the occurrence and co-occurrence of chronic conditions, functional limitations, and geriatric syndromes. Results: In a sample of 18 913 participants (weighted n = 87.5 million), 1.93% and 1.84% presented with mild and moderate/severe CI, respectively. The prevalence of most conditions constituting complex MM increased markedly across the spectrum of CI. Further, the percentage of individuals presenting with 10 or more conditions was 19.9%, 39.3%, and 71.3% among those with no CI, mild CI, and moderate/severe CI, respectively. Discussion: Greater CI is strongly associated with increased burden of complex MM. Detailed characterization of MM across CI gradients will help identify opportunities for health care improvement.
KW - chronic conditions
KW - cognitive impairment
KW - functional limitations
KW - geriatric syndromes
KW - multimorbidity
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U2 - 10.1177/1533317517726388
DO - 10.1177/1533317517726388
M3 - Article
C2 - 28871795
AN - SCOPUS:85030858079
SN - 1533-3175
VL - 32
SP - 408
EP - 417
JO - American Journal of Alzheimer's Disease and Other Dementias
JF - American Journal of Alzheimer's Disease and Other Dementias
IS - 7
ER -