Induction of implantation by androgens in mice with delayed implantation.

S. K. Roy; J. SenGupta; S. K. Manchanda

doi:10.1530/jrf.0.0580339

Induction of implantation by androgens in mice with delayed implantation.

S. K. Roy, J. SenGupta, S. K. Manchanda

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Testosterone and 5 alpha-dihydrotestosterone (5 alpha-DHT) were able to mimic the action of oestradiol-17 beta in initiating implantation in ovariectomized, progesterone-treated mice. Cyproterone acetate and CI-628 were capable of inhibiting the testosterone-induced response, but CI-628 citrate prevented only the 5 alpha-DHT-mediated implantation reaction. It is suggested that testosterone acts through testosterone and oestrogen receptors while 5 alpha-DHT acts only through oestrogen receptors.

Original language	English (US)
Pages (from-to)	339-343
Number of pages	5
Journal	Journal of reproduction and fertility
Volume	58
Issue number	2
DOIs	https://doi.org/10.1530/jrf.0.0580339
State	Published - Mar 1980
Externally published	Yes

ASJC Scopus subject areas

Physiology
Embryology
Molecular Biology
Obstetrics and Gynecology
Developmental Biology

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year = "1980",

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AB - Testosterone and 5 alpha-dihydrotestosterone (5 alpha-DHT) were able to mimic the action of oestradiol-17 beta in initiating implantation in ovariectomized, progesterone-treated mice. Cyproterone acetate and CI-628 were capable of inhibiting the testosterone-induced response, but CI-628 citrate prevented only the 5 alpha-DHT-mediated implantation reaction. It is suggested that testosterone acts through testosterone and oestrogen receptors while 5 alpha-DHT acts only through oestrogen receptors.

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Induction of implantation by androgens in mice with delayed implantation.

Abstract

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