Induction of implantation by androgens in mice with delayed implantation.

S. K. Roy, J. SenGupta, S. K. Manchanda

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Testosterone and 5 alpha-dihydrotestosterone (5 alpha-DHT) were able to mimic the action of oestradiol-17 beta in initiating implantation in ovariectomized, progesterone-treated mice. Cyproterone acetate and CI-628 were capable of inhibiting the testosterone-induced response, but CI-628 citrate prevented only the 5 alpha-DHT-mediated implantation reaction. It is suggested that testosterone acts through testosterone and oestrogen receptors while 5 alpha-DHT acts only through oestrogen receptors.

Original languageEnglish (US)
Pages (from-to)339-343
Number of pages5
JournalJournal of reproduction and fertility
Volume58
Issue number2
DOIs
StatePublished - Mar 1980

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ASJC Scopus subject areas

  • Physiology
  • Embryology
  • Molecular Biology
  • Obstetrics and Gynecology
  • Developmental Biology

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