Infected total knee arthroplasty: diagnosis and treatment.

Kevin L. Garvin, Gustavo X. Cordero

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


Infection following total knee arthroplasty is a challenging complication for both the patient and the surgeon. Precautions to prevent infection include the use of prophylactic antibiotics, minimized surgical time, and meticulous surgical technique. A patient's risk factors should be thoroughly assessed and medical comorbidities should be treated before surgery. When infection is suspected, prompt evaluation of the patient is necessary. The management of a TKA infection is dictated by the duration of symptoms, suspicion for infection, time since index surgery, the patient's willingness and medical capability for undergoing multiple surgeries, the bacteria's sensitivity to antibiotics, and the surgeon's ability to perform complex surgery. Acute infections are treated with aggressive débridement and parenteral antibiotics. In appropriate circumstances, chronic infections are best treated with two-stage reimplantation, which can reliably eradicate infection, relieve pain, and restore good function.

Original languageEnglish (US)
Pages (from-to)305-315
Number of pages11
JournalInstructional course lectures
StatePublished - 2008

ASJC Scopus subject areas

  • General Medicine


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