Infection and immune response in the elderly

Philip W. Smith; Jane S. Roccaforte; Pamela B. Daly

doi:10.1016/1047-2797(92)90075-2

Infection and immune response in the elderly

Philip W. Smith, Jane S. Roccaforte, Pamela B. Daly

Infectious Diseases

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

A number of immunologic functions have been shown to decline in an age-related fashion, particularly cell-mediated immunity and antibody response to an immunogen. Underlying degenerative diseases and medications further contribute to the immunologic abnormalities noted in the elderly. The elderly in hospitals and nursing homes are a particularly vulnerable subset, with a high incidence of institutionally acquired infection. Aspects of disease prevention in the elderly are discussed.

Original language	English (US)
Pages (from-to)	813-822
Number of pages	10
Journal	Annals of Epidemiology
Volume	2
Issue number	6
DOIs	https://doi.org/10.1016/1047-2797(92)90075-2
State	Published - Nov 1992

Keywords

Elderly
immunity
immunosenescence
infection

ASJC Scopus subject areas

Epidemiology

Access to Document

10.1016/1047-2797(92)90075-2

Cite this

@article{45b544086c4c4f1b955db5c54f45ab3b,

title = "Infection and immune response in the elderly",

abstract = "A number of immunologic functions have been shown to decline in an age-related fashion, particularly cell-mediated immunity and antibody response to an immunogen. Underlying degenerative diseases and medications further contribute to the immunologic abnormalities noted in the elderly. The elderly in hospitals and nursing homes are a particularly vulnerable subset, with a high incidence of institutionally acquired infection. Aspects of disease prevention in the elderly are discussed.",

keywords = "Elderly, immunity, immunosenescence, infection",

author = "Smith, {Philip W.} and Roccaforte, {Jane S.} and Daly, {Pamela B.}",

year = "1992",

month = nov,

doi = "10.1016/1047-2797(92)90075-2",

language = "English (US)",

volume = "2",

pages = "813--822",

journal = "Annals of Epidemiology",

issn = "1047-2797",

publisher = "Elsevier Inc.",

number = "6",

}

TY - JOUR

T1 - Infection and immune response in the elderly

AU - Smith, Philip W.

AU - Roccaforte, Jane S.

AU - Daly, Pamela B.

PY - 1992/11

Y1 - 1992/11

N2 - A number of immunologic functions have been shown to decline in an age-related fashion, particularly cell-mediated immunity and antibody response to an immunogen. Underlying degenerative diseases and medications further contribute to the immunologic abnormalities noted in the elderly. The elderly in hospitals and nursing homes are a particularly vulnerable subset, with a high incidence of institutionally acquired infection. Aspects of disease prevention in the elderly are discussed.

AB - A number of immunologic functions have been shown to decline in an age-related fashion, particularly cell-mediated immunity and antibody response to an immunogen. Underlying degenerative diseases and medications further contribute to the immunologic abnormalities noted in the elderly. The elderly in hospitals and nursing homes are a particularly vulnerable subset, with a high incidence of institutionally acquired infection. Aspects of disease prevention in the elderly are discussed.

KW - Elderly

KW - immunity

KW - immunosenescence

KW - infection

UR - http://www.scopus.com/inward/record.url?scp=0027048348&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027048348&partnerID=8YFLogxK

U2 - 10.1016/1047-2797(92)90075-2

DO - 10.1016/1047-2797(92)90075-2

M3 - Article

C2 - 1342334

AN - SCOPUS:0027048348

SN - 1047-2797

VL - 2

SP - 813

EP - 822

JO - Annals of Epidemiology

JF - Annals of Epidemiology

IS - 6

ER -

Infection and immune response in the elderly

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this