TY - JOUR
T1 - Infectious complications during autotransplantation
AU - Reed, E. C.
PY - 1993
Y1 - 1993
N2 - Bacterial and fungal infections are the most common cause of morbidity and mortality following autologous marrow transplant. An understanding of defects in host defense and the sources of bacterial and fungal infections allows a rational approach to controlling infections through prophylactic and empiric treatment. Recent availability of growth factors, broad-spectrum antibiotics, monoclonal antibodies to endotoxin, new antiviral agents, and new antifungal agents have enhanced our ability to successfully support patients through high-dose therapy and autologous stem cell reinfusion.
AB - Bacterial and fungal infections are the most common cause of morbidity and mortality following autologous marrow transplant. An understanding of defects in host defense and the sources of bacterial and fungal infections allows a rational approach to controlling infections through prophylactic and empiric treatment. Recent availability of growth factors, broad-spectrum antibiotics, monoclonal antibodies to endotoxin, new antiviral agents, and new antifungal agents have enhanced our ability to successfully support patients through high-dose therapy and autologous stem cell reinfusion.
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U2 - 10.1016/s0889-8588(18)30239-9
DO - 10.1016/s0889-8588(18)30239-9
M3 - Article
C2 - 8344887
AN - SCOPUS:0027159146
VL - 7
SP - 717
EP - 735
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
SN - 0889-8588
IS - 3
ER -